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Infection > Lecture 3 > Flashcards

Lecture 3 Flashcards

1
Q

How is normal flora displaced

A

Breach of skin e.g surgery, IV, trauma
Poor dental hygiene - haematogenous spread
Faecal -oral route
Fecal- perineal - urethral route

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2
Q

High risk patients

A 
Asplenic 
Immunocompromised - diabetes, AIDS, malignancy
Infective Endocarditis
Damaged or prosthetic valves 
Normal flora depleted by drugs
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3
Q

Which conditions decrease neutrophil count

A

Chronic granulomatous disease - no resp burst

Chediak - Higashi syndrome - no phagolysosome formation

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4
Q

Till receptor for lipopolysaccharide

A

TLR4

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5
Q

Toll like receptor for peptidoglycan

A

TLR2

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6
Q

Toll like receptor for flagella

A

TLR5

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Infection (10 decks)

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