Streptococci Flashcards
1
Q
Streptococcus pyogenes virulence factors
A
M protein Hyaluronic acid capsule Adhesins Streptolysin DNAses Hyaluronidase Streptokinase Streptococcal pyrogenic exotoxin
2
Q
Hyaluronic acid capsule
A
Inhibits phagocytosis by neutrophils and macrophages pure immunogen because of similarity to human connective tissue
3
Q
M protein
A
Prevents phagocytosis by neutrophils and macrophages by inhibiting activation of the complement pathway on the bacterial cell surface
4
Q
Adhesins
A
Adherence
5
Q
Streptolysins O and S
A
Lysis of erythrocytes, neutrophils and platelets
6
Q
DNAses A, B, C , D
A
Degradation of DNA
7
Q
Hyaluronidase
A
Degradation of hyaluronidic acid in human connective tissue
8
Q
Streptokinase
A
Dissolution of clots by converting plasminogen to plasmin
9
Q
Streptococcal pyrogens exotoxin
A
Cleaves IgG from Group A strep
10
Q
Complication of strep pyogenes
A
Streptococcal pharyngitis Scarlet fever Suppurative infections - abscesses Acute rheumatic fever Acute glomerulonephritis Toxic shock syndrome Necrotising fasciitis Impetigo Cellulitis
