Travel Med Flashcards
2500 m = _____ ft
8000
Acute Mtn Sickness- alttude
2500 m (8000 ft)
Aedes vector for 5 virus CRuDZY
DEN, CHIK, YF, RVF, Zika
After dive, avoid flying for:
>12 h after no-compression dive >18 h after repetitive or after decompression diving >24 h after altitude diving
after drop effect
Core temp drop if blood flow to extremities first -> repurfusion acidosis
airline and cruise EGA restrictions
32-36 air, 28 boat
altitude and pregnancy (2)
try to sleep below 3600 m NO acetazolamide
Anopheles vector for
malaria, ONY
Arterial gas embolism- cause, timing
lung barotrauma causing CVA and MI with 10 min of surfacing; cause 3% dive deaths
Bartonella- 3 types, vectors, disease
B. bacilloformis – sand fly- bartonellosis B. henselae- flea- cat scratch, bacillary angiomatosis, endocarditis B. quintana- louse- trench fever, endocarditis, bacillary angiomatosis
BCG side effects
ulcer or abscess weeks later
Bismuth reduces travelers diarrhea by
55% take QID
black fly vector for (3)
onchocerciasis, M. Ozzardi, dirofilariasis
Cholera vaccine- indication
epidemics 2 doses 1-6 weeks apart (depending on type age down to 1 or 2)
Chrysops deerfly vector for (2)
Loa, Francisella tularensis
Ciguatera poisoning- agent, source, sx (2), Tx
Gambierdiscus toxicus (a flagellate) heat resistant
gastroenteritis/vomit 1-6 hours; paresthesias, pruritis and myalgia may persist months
hot/cold reversal
warm-water reef fish, oysters, clams
supportive Tx
Contraindication to DTaP
Encephalopathy within 1 week of previous DTaP/DTP
Contraindication to Hep A
Anaphylactic reaction to 2-pheooxyethanol or alum
Contraindication to IPV
Anaphylactic reaction to neomycin, streptomycin or polymyxin B
contraindications to MMR
reaction to prior MMR, Immunosuppression, Thrombocytopenia, Gelatin or neomycin allergy, Pregnancy
Contraindications to nasal flu (4)
< 2 YO, egg allergy, lung disease, pregnant
Culex vector for
LF, JE, WNV, VEE, WEE, EEE
DDx subconjunctival hemorrhage (4)
Leptospirosis, scrub typhus, hantavirus renal, dengue, measles
decompression illness
Inadequate elimination of nitrogen from tissues during ascent, causing muscle aches and pains
Decompression sickness
nitrogen bubbles forming in tissues on resurfacing- cause 2% dive deaths
DEET can also inhibit (2)
schisto, tick (typhus)
elderly less likely to get (3)
motion sickness, diarrrea, AMS
Flea is vector for (6)
Bacteria: B. henslae, R. felis, R. typhi, Y. pestis Parasite: Dipylidium caninum, tungiasis
frequency of post-infectious IBS
25%
frostbite- def, Tx, good prognosis
ice crystals in tissue rapid rewarm, avoid refreeze early clear blebs and edema
Glossina Tsetse fly vector for
Trypansomsoma brucei
Hajj- attendees, illnesses (lung, blood, nasal)
3 million from > 180 countries 75% get Hajj cough- environmental, TB, flu, pneumonia, MERS HIV and hepatitis from shaving by barbers PAM- nasal abolution
health contraindications to fight
10 days after chest or abdominal surgery 14 days from MI or CABG Uncontrolled CHF, Sz, HTN, DM, psych
health precautions to flying (4)
Anemia Cerebrovascular disease SS Pulmonary- dry cabin air
heat exhaustion vs heat stroke
weak, confusion vs collapse, uncontrolled fever, organ damage
Hep A vaccine use in endemic?
No. Kids usually mild and Asx.
Hepatitis B vaccine contraindications (2)
previous allergy, yeast allergy
High altitude cerebral edema (HACE)- Sx, Tx
Sx: ataxia, confusion Tx: immediate descent. Dexamethasone may buy time
High altitude contraindications
Uncontrolled CHF, pulm HTN, SS, mod-severe COPD (not asthma); Hx HAPE, HACE
High Altitude Pulmonary Edema (HAPE)- fame, Tx
most common cause of altitude death descent, O2, EPAP, nifedipine (steroid NO help)
high eosinophlilia related to
trichinosis, visceral larva migrans, microfilaria, onchocerciasis, ascariasis, hookworm, schistosomiasis, or liver or lung flukes
HIV malaria prophylaxis interaction
mefloquine and ART
how effective is 1st dose of measles
97%
how long for meningitis, YF and polio to be effective
10 d, 10 d, 4 wks
how long until YF vaccine effective
10 d
how often are diarrhea studies positive- what percentages
1/3 pos 70% bacterial, 15% viral
HPV strains related to CA, related to warts, in vaccine
16, 18, 31. 33 6, 11 (6, 11,) 16. 18
Huntington’s response
cold induced vasodilation in intermittent 5-10 min cycle at 10 degrees C
hyperthermia
>40
hypothermia
< 35
hypothermia levels
< 35 mild (passive rewarming), < 33 moderate (active rewarming), < 28 severe (stop resuscitation at 32 if no response)
immersion injury
non-freeze cold injury like trench foot
Immunization contraindicated in pregnancy
MMR, VZV, other live
Immunization in immunocompromised (3)
no BCG regardless no YF IF symptomatic HIV maybe no roto IF symptomatic HIV
Infections from animal bites (5)
rabies, tetanus, pasteurellosis, bartonella, herpes B virus…
jellyfish stinger removal and Tx
credit card, sea water, Windex, vinegar (anemone and coral also have neumatocysts); box jelly antivenom (AUS)
live typhoid coverage vs IM
Paratyphoid B but not A
Live vaccines- 9
MMR, OPV, Yellow fever, Vaccinia, Varicella, Nasal influenza, BCG, Cholera, Oral typhoid
Louse vector for (3)
Epidemic typhus (R. prowazekii) Trench fever (B. quintana) Relapsing fever (Borrelia recurrentis)
lower age limits on sunscreen, DEET
6 mo, 2 mo
Malaria emergency Tx
Malarone 4 tabs x 3 d Artemether/lumefantine (Coartem) 4 tabs for 6 doses Mefloquine 250 mg- 3 tabs, then 2 tabs 6-12 h later
malaria prophylaxis and breast feeding
any
Measles vaccine contraindications
pregnancy, severe immunocompromised neomycin or gelatin allergy (OK egg allergy) thrmobocytopenia
measles vaccine side effects
10% get rash week later 1/3000 have Sz
mefloquine black box warning
dizzy may be permanent, psych may persist yrs
Menactra and Menveo cover which strains
A, C, Y, W135
midge/culicoides vector for
mansonella
MMR timing for travelling infant
6 mos, repeat in 1 month if still travelling
mosquito day biter infections (2)
dengue, chik
mosquito night biter infections (3)
malaria, WNV, JE
Most common malaria in travellers
vivax
myiasis vs tungiasis
African tumbu/botfly Sand flea
nasal flu contraindications
< 2 YO asthma/COPD pregnancy/immunocompromised (NO egg issue)
Neurotoxic shellfish poisoning- source, Sx
Red tide dinoflagellate concentrating in shellfish, ingest or inhaled wave GI, paraesthesia, ataxia
Nitrogen narcosis/ depth, Tx
depths greater than 70 ft or 100 ft clears on resurfacing.
Norovirus- incubation, duration, spread
1-2 d < 4 d FO, P2P, fomites
number traffic deaths annually
1.3 million
only required vaccines
YF for certain countries in AF and SAM Meningitis for Mecca polio before leaving a few endemic areas (Cameroon, Pakistan, Syria)
OPV risk
1/250K get paralytic polio use IPV in low endemic areas
osborne J wave
on EKG, notched R wave wider than RBBB
Paralytic shellfish poisoning- agent, source, onset, Tx
Dinoflagellate- concentrated in mollusk so Shellfish, seafood Potent toxin
percent sulfa allergy getting rash with acetazolamide
7%
permethrine can also inhibit (2)
tick (typhus), triatomine (Chagas)
Pigbel vaccine- target, geo, schedule
to Clostridium perfringens toxin type 3 used in Papua New Guinea 2, 4, 6 mo
pregnancy stand by malaria Tx
malarone x 3 d
pregnancy travel contraindications
multiple, malpresentation, hyperemesis, FGR, abruption, active labor, cervical incompetence, PTL, PROM, ectopic, toxemia
preventing malaria in first pregnancy in Africa
sulfadoxine/pyrimethamine at prenatal visits
Resistant to alcohol
Cryptosporidium, norovirus, anthrax
Sand fly/phlebotmus vector for (3)
leishmania sand fly fever Bartonella bacilliformis
scombroid poisoning- Sx, source, signs
histidine in fish causing allergic reaction heat resistant only prevention is to store fish properly tuna, mackerel, bonito, skipjack and canned fish may describe a peppery, salty, or spicy taste
sea urchin spine removal and Tx
surgical, hot water (heat labile toxin)
stool studies for chronic diarrhea
O+P AF for cryptosporidia, cyclospora, isospora Giardia Ag C. dif toxin
tetrodotoxin
neurotoxin from puffer/fugu
Tick vector for
viral: CCHF, TBE, KFD, OMSK, POW, CTF Bacterial: Lyme, Borrelia, Ricketsial (Spotted, Q fever), tularemia Dermacentor (RMSF, CTF, tularemia, Siberian tick typhus, tick paralysis) Ixodes (Lyme, babesia, human granulocytic ehrlichiosis,)
Transplant pts and vaccines
avoid live for 2 yrs and other for 3-6 mo
travel health risks per 100K
1 death 300 hospital 8000 see doc 50% some health issue
travel mortality- top 2, bottom
45% CV 25% accident 1% ID
Travelers diarrhea- geo
Latin Americia- EAEC Asia- Campylo, Plesiomonas, Aeromonas Africa- Aeromonas
Travelers diarrhea- incidence, peaks, duration, incubation
Incidence 35% per 2 weeks Peak days 2-4 and 10-12 d Duration 2-5 d bacterial or viral Incubation , 4 d
Triatomine bug vector for
Trypanosoma cruzi/Chagas
Tropical sprue- geo, cause, Tx
Asia, SAM ? doxy 6 wks with folate
Tropical Sprue- geo, Sx, Tx
chronic diarrhea from Asia, South America Malabs, B12 and folate def, steatorrhea No causative agent found Responds to 6 weeks TTC and folate
Tularemia- 5 presentations
Ulceroglandular, Glandular, Oculoglandular, Oropharyngeal, Pneumonic
typhoid vaccine re-booster
oral- 5 yrs IM- 2 yrs
typhoid vaccines lower age limit (2)
IM 2 YO, PO 6 YO
Vaccine best for wild type polio
Oral Sabin vaccine
vaccines safe to give at birth (2)
Hep B, OPV
vaccines to avoid with 2-pheooxyethanol or alum allergy
Hep A
vaccines to avoid with egg allergy (3)
JE, flu, YF
vaccines to avoid with gelatin allergy (2)
MMR, YF
vaccines to avoid with neomycin allergy (3)
IPV, MMR, Hep A, some Hep B, some flu, smallpox
vaccines to avoid with streptomycin or polymyxin B allergy
IPV
vaccines to avoid with yeast allergy
Hep B
Venomous fish- examples, Tx
includes Scorpionfish, Stonefish, Lionfish, weeverfish, stingray, catfish (Indo-Pacific) Tx hot water, stonefish antivenom (AUS)
What insect is attracted to bright blue colors
Tsetse, Glossina
what percent people on malaria prophylaxis still get malaria?
6%
WHO rabies PEP Categories and Tx
I- touch,lick; none II- scratch with no bleeding; vaccine III- bites, mucous mems, bats; RIG and vaccine
Yellow fever contraindications and precautions
YFV contraindications: < 6 mos Immunodeficiency- CD4 < 200, Thymus disorder, Cancer, Transplant Allergy to egg, gelatin, latex YFV Precautions: 6-9 mos, Age > 60 YO ASx HIV with CD4 200-500 Pregnant BF
Yellow fever lower age limit
6 mo with precaution, 9 mo without
Yellow fever vaccine complications
YEL-AND (neuro)- about 1/100K but higher in elderly YEL-AVD (viscerotropic)- 0.4/100K, higher in elederly, 60% mortality
YF vaccine in HIV
CD4 < 200 contraindicated < 500 precaution