Traumatic Brain Injury Flashcards

1
Q

What are signs of TBI?

A
Deteriorating mental status
CSF otorrhea or rhinorrhea
Seizures
Abnormal breathing pattern
Unstable VS
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2
Q

What are sx of TBI?

A
Loss of consciousness
Amnesia
Dizziness
HA
N/V
Limb weakness
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3
Q

What are lab/diagnostics for TBI?

A
BMP
ABG
Urine drug screen
Blood alcohol screen
CT
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4
Q

What is a primary brain injury?

A

Occurs at the time of trauma

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5
Q

What is a secondary brain injury?

A

Occurs from time of event to ours and days after trauma

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6
Q

What are the scales for TBI classification?

A
15 = normal
13-15 = mild brain injury
9-12 = mod brain injury
3-8 = severe brain injury
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7
Q

What are TBI treatment goals?

A
CAB
Minimize secondary neuronal injury
Monitor and manage intracranial pressure
Seizure prophylaxis/treatment
Medical management
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8
Q

What is the primary goal of initial resuscitaiton?

A

Prevent hypotension and hypoxia

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9
Q

What is CAB?

A

Secure airway, ensure adequate oxygenation

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10
Q

How do we maintain blood flow to brain and other organs?

A

Crystalloids
Vasopressors PRN after restoration of intravascular volume
Blood products when available

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11
Q

How do we calculate CPP?

A

MAP - ICP

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12
Q

How do we calculate MAP?

A

(SBP + 2xDBP)/3

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13
Q

What is goal CPP?

A

50-70

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14
Q

What is goal ICP?

A

<20

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15
Q

What are methods to lower ICP?

A

Elevated head of bed 30+ degrees
Sedation, analgesics, anxiolytics
Avoid hyperventilation
Ventricular drainage of CSF

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16
Q

What is the DOC for lowering ICP d/t pain, agitation, resting mechanical ventilation?

A

Propofol

17
Q

What drugs are used for sedation, analgesia, and anxiety?

A

Propofol
Opioids (fentanyl)
Benzos (midazolam)

18
Q

What is used for osmotic therapy?

A

Mannitol

19
Q

Why is mannitol used?

A

Diuretic to decrease ICP

20
Q

Why is hypertonic saline used?

A

Decrease ICP

21
Q

What is a last ditch effort and used in refractory ICP?

A

Barbiturates

22
Q

What drugs are used for seizure prophylaxis?

A

VPA

Phenytoin

23
Q

How long are AEDs used for?

A

7 day prophylaxis

24
Q

What can accelerate functional recovery?

A

Amantadine

25
Q

What is a neuroprotectant?

A

Allopregnanolone