Trauma/Critical Care Flashcards
What’s the difference between a shunt vs. Dead space?
Shunt: (+) blood flow / (-) aeration
Dead space: (-) blood flow / (+) aeration
What is the PaO2 that defines failure to oxygenate?
What PaCO2 defines failure to ventilate?
PaO2 < 60
PaCO2 > 55
Mechanical ventilation safe lung strategy
Tidal volume less than what?
Plateau pressure less than?
Permissive hypercapnia up to how much?
Tidal volume <6cc/kg
Plateau pressure <30mmHg
Permissive hypercapnia up to pH7.2
What’s the difference between ALI vs. ARDS?
ALI: PaO2 to FiO2 ratio <300
ARDS: PaO2 to FiO2 ratio <200
What do NSAIDs do for renal afferent/efferent vasculature?
What does hypotension do for renal perfusion?
NSAIDs: inhibit afferent vasodilation (afferent constriction)
Hypotension: afferent constriction, efferent dilation
What’s the lifespan of RBC’s?
Lifespan of platelets?
Lifespan of wbcs?
RBC’s: 120 days
Platelets: 8-9 days
Wbcs: 1-2 days
What are the five grades of pancreatic trauma? How do you treat them?
[T/F] grade III pancreatic injury can be managed non-operatively
I: minor contusion
II: major contusion without ductal injury
- non-op
III: distal transection
- distal panc
IV: proximal transection
- drain + post-op ERCP
For grades III and IV non-op management has higher complication rate. so they need an exploration if discovered on imaging
V: massive disruption of the pancreatic head
- DRAIN DRAIN DRAIN
What’s the grading system for blunt injuries to the duodenum?
I: hematoma or laceration without perforation
II: disruption <50% circumference
III: disruption 50-75% circumference
IV: >75% circumference involving the ampulla/distal CBD
- primary repair
V: massive disruption of the duodenopancreatic complex or duodenal devascularization
Blunt trauma, rib fx non-op vs rib fixation
- narcotic requirement
- cost
- ventilator days
- pneumonia
- mortality
Who should be considered for rib fixation, when is the optimal timing?
No difference in narcotic requirement Rib fixation is more expensive Rib fixation reduces ventilator days Rib fixation reduces pneumonia rate No difference in mortality
People who can’t be weaned off of ventilator. Maximum benefit within 3-5 days
If Pringle slows down the bleeding, what does it mean? Where is the injury?
What might you consider for repair if Pringle works?
It means IVC and hepatic veins are probably fine.
Consider hepatic artery ligation
What complication may occur if you ligate the hepatic artery?
Abscess or a biloma
Surgical airway in a 13 yr old. What do you do?
Cricothyroidotomy for kids 12 or older.
For kids younger than 12 -> 12, 14, 16 gauge needle airway
Neck stab wound. Carotid artery injury found during exploration. What do you do in general?
What to do if the defect >2cm? Use prosthesis?
What about a high carotid injury- how do you expose?
Generally primary repair. Prolene
2>cm use saphenous vein graft. Prosthesis is avoided generally for long term patency
High carotid- divide the digastrics, subluxation of the mandible
Neck stab wound. Esophageal injury. How do you repair it?
What if it’s hard to locate the injury?
What if it’s been more than 24 hrs?
NG tube. Can use methylene blue to identify hole. Close in two layers, absorbable suture
> 24hrs then esophagostomy, feeding tube, tissue buttress
Neck stab wound. Tracheal injury. What do you do?
What if a tracheostomy is needed? Through the same hole?
Repair with interrupted absorbable sutures muscle buttress
Never through the same hole
Neck stab wound. Vertebral artery injury. What do you do?
IR embolize
Neck stab wound. Big vein injury. IJ. Use a graft to repair? Why or why not
Graft will thrombose. Just ligate the vein
Odontoid fx types. I, II, III
Which one tends to be painful?
Which type may have airway compromise due to swelling?
Painful: type I
Airway: type II
Cardiac tamponade pathophys.
What are the two pressures at war here? What’s the endpoint?
How many phases?
Cardiac output starts to get affected when?
Initial signs of shock becomes evident in what phase?
Intrapericardial pressure vs. ventricular DIASTOLIC filling pressure. Endpoint is when these two pressures become the same. Phase 3
3 phases
Cardiac output is maintained during phase I with tachycardia & increased SVR. Phase II cardiac output goes down.
Signs of shock at phase II
ED thoracotomy
- which intercostal space?
- how many joules to defribrillate after EDT? How many Joules to externally defib?
- to Foley or not to Foley?
5th intercostal space
15-30J to internally defib. 100-200J for external defib
Don’t Foley because it can tear the defect, make it bigger
Resuscitation goals for
Plt
INR
Fibrinogen
T
Plt > 100k
INR < 1.2
Fibrinogen > 100
T > 37 (98.6)
Define pancreatic leak
What’s considered a minor fistula vs. high output.
Drain amylase > serum x3
Minor fistula < 200cc/day
High output > 700cc/day
Boundary of posterior neck triangle
Sternocleido anteriorly
Trapezius posteriorly
Clavicle at the base
Neck stab wound. Totally stable, no crepitus, no dysphagia, no dysphonia. Small 2cm sound. Non-op management. Still do CTA? Chest XR? Barium swallow?
Yes to all. Every neck wound if non-op, get everything
What are some differences between superficial second degree burn vs. Deep second degree burn?
Superficial second degree
Wet
Pink
Deep second degree:
Dry
More pale than pink
When doing a nephrectomy, what are the tributary vessels to renal vein? Do you divide the vein first or the artery first?
Gonadals, lunbars, adrenals.
Divide these three to mobilize the renal vein. You need to mobilize the vein in order to obtain control of the renal artery.
Divide the artery first then divide the renal vein to prevent renal congestion
Mild, moderate, severe traumatic brain injury: what is the diagnosis based on?
What is the most prevalent type?
What % of moderate TBI will develop into severe TBI?
What is the mortality rate of severe TBI?
What % of mild TBI will have an identifiable lesion on CTH?
Who needs ICU?
GCS 13-15: mild TBI
GCS 9-12: moderate TBI
GCS <8: severe
Mild is the most prevalent (80%)
12% of moderate TBI becomes severe
20% mortality rate for severe TBI
10-30% of mild will have CTH lesion
All moderate to severe TBI needs ICU. GCS <12
Externally rotated leg. Abducted.
What dislocation? What associated injury?
Anterior disloc
Femoral vein thrombosis
Internally rotated leg, adducted
What dislocation? What associated injury?
Posterior dislocation. Sciatic nerve inj
Distal radius fracture. What nerve?
Median nerve
Mid humerus fx. What nerve!
Radial
Supracondylar humerus fx. What injury?
Distal humerus fx
Brachial artery
Volksmann ischemic contracture
Anterior shoulder dislocation. What injury?
Axillary nerve
Spenic lac grade. % surface area hematoma & cm?
What’s the failure rate for conservative management?
Grade I: <10% hematoma, <1cm deep lac
5%
Grade II: 10-50% hematoma, 1-3cm deep lac
10%
Grade III: >50% hematoma, >3cm deep
20%
Grade IV: laceration involving hilum, major devascularization
33%
Grade V: shattered spleen
75%
Most common bacterial organisms in human bite? What’s the first line treatment?
Which bites more likely to cause tenosynovitis? Dog? Cat? Human?
First line treatment for animal bites?
Staph aureus, strep. Cephalosporin
Cat bites: tenosynovitis
Animal bites: augmentin (amox-clav)
What are the different phases of empyema?
What % of empyema are culture positive?
When/how many days is an operation needed?
Acute(7d), subacute, chronic
20-30% not culture (+)
After 7d
Post ruq stab wound biloma.
- what volume from the drain suggests you should operate?
- most are intra- extrahepatic bike duct injury?
- persistent drainage >50cc/day -> what’s the diagnosis? What’s the treatment
- > 300/day operate
- most are to intrahepatic ducts
- biliary fistulas. Usually resolve without treatment
What is the complication rate for chest tube?
Is bigger chest tube 36-40Fr better than smaller chest tube for hemothorax?
What’s the Hounsfield unit for hemothorax?
If hemothorax is < ____ cc then chest tube shouldn’t be placed
Abx for traumatic chest tube?
25%.
Tube size apparently doesn’t matter.
Hounsfield unit 35-70
300cc
No abx
What is Rivaroxaban?
What’s the reversal agent?
Does dialysis work?
Xarelto
Factor Xa inhibitor
Andexanet Alfa
Dialysis doesn’t work because it highly binds to proteins
Dabigatran. What is it?
How do you reverse?
Pradaxa
Direct thrombin inhibitor
Dialysis or idarucizumab (monoclonal antibody)
What are the components of the Berlin definition of ARDS? What are the mortality rates based on mild moderate severe ards?
PaO2/FiO2 200-300 mild aka ALI ~25% mortality
PaO2/FiO2 100-200 moderate ~32% mortality
PaO2/FiO2 <100 severe ~45% mortality
Need to have PEEP @ 5
Hypoxia must occur 7 days after the insult
Caloric requirement for critically ill?
Protein requirement for critically ill?
25-30kcal/day
1.5-2g/kg/day
What is the Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition diagnostic criteria for malnutrition?
Involuntary loss of >10% body weight in 6 months
Or
5% body weight loss in 1 month
Up to how many tracheal rings in length can be repaired primarily?
Best way to gain access to distal tracheal injury?
Up to 5 or 6 tracheal ring length
Right posterolateral thoracotomy provides the best access to the distal intrathoracic trachea
What incision for proximal control of right subclavian artery?
Median sternotomy
What incision for proximal control of left subclavian artery?
what about for exposure of an injury 1cm distal to left subclavian takeoff?
Anterior thoracotomy in the third intercostal space
for aortic injury distal to subclavian takeoff -> Left posterolateral thoracotomy
When to use infraclavicular vs. Supraclavicular incisions for subclavian artery injury?
Infraclav: distal control of the subclavian artery
Supraclav: for repair of the vessel
Mechanical ventilation safe lung strategy
Tidal volume less than what?
Plateau pressure less than?
Permissive hypercapnia up to how much?
Tidal volume < 6mL/kg
Plateau pressure < 30mmHg
Permissive hypercapnia up to pH 7.2
What’s the difference between ALI vs. ARDS?
ALI: PaO2 to FiO2 ratio <300
ARDS: PaO2 to FiO2 ratio <200
Where is calcium absorbed?
How is it absorbed? Active or passive?
Duodenum & jejunum
It binds to calbindin which then transfers it to the basal membrane. Then it actively gets pumped in.
Active transport in the duodenum
Passive transport in jejunum > ileum
Indication for therapeutic hypothermia (TH)
What T?
When should you stop?
pts who fail to awaken after cardiac arrest
T 32-34C (89.6-93.2F) for 12-24 hrs after ROSC
Hypotension + hgb decrease by 3
1 cause of exudative pleural effusion?
What % of pneumonia have associated effusion? What % of those effusions will develop into empyeme?
What are the stages of empyema?
What type of organism is most common in empyema?
1 is malignancy
Up to 50% of pneumonia have effusion. Only ~5% of them will develop into empyema
Stage I: EXUDATIVE stage. Fluid is thin, lights, low wbc count, low LDH
Stage II: FIBRIN PURULENT stage. Fluid becomes infected. LDH and WBC increase. Glucose and pH drop. Lung is often unable to expand
Stage III: ORGANIZING stage. Think pleural peel created by migrating fibroblasts -> DECORT
Used to be strep pneumo, now anaerobes.
What are the components of vital capacity?
Inspiratory reserve volume + tidal volume + expiratory reserve volume
Inspiratory capacity = inspiratory reserve volume + tidal volume
What is inspiratory capacity?
Tidal volume + inspiratory reserve volume
What is FRC?
Functional residual capacity = expiratory reserve volume + residual volume
Total lung volume - inspiratory capacity
Total lung volume - inspiratory reserve volume - tidal volume
Inspiratory capacity = inspiratory reserve volume + tidal volume
4 components of total lung capacity?
Inspiratory reserve volume + tidal volume + expiratory capacity + residual volume
Respiratory quotient of pure carb metabolism
1
Respiratory quotient of pure protein metabolism
0.8
Respiratory quotient of pure fat metabolism
0.7
What does RQ > 1 mean vs. RQ < 1?
> 1 means overfeeding glucose/fat
<1 means ketogenesis
Free water deficit equation
(pt sodium - ideal Na) / ideal Na x total body water in L
Total body water = pt weight in kg x gender factor (0.5 for women, 0.6 for men)
Normal ICP?
7-15 mmHg
When to transfuse platelets for
- hospitalized adult pt to reduce spontaneous bleeding
- surgery
- for central line
- hospitalized adult pt to reduce spontaneous bleeding: < 10 x10^9
- surgery: < 50 x 10^9
- for central line: < 20 x 10^9
What’s p Delta in compartment check?
What’s the threshold for fasciotomy?
DBP - compartment pressure
< 20-30 mmHg usually indicates fasciotomy
top 3 Most common hospital acquired infection?
#1: hospital acquired pneumonia 25-48% #2: surgical site infxn 24% #3: UTI 14%
Most common fungal pulmonary infection? Treatment.
Histoplasmosis, itraconazole
What is apixaban
mechanism?
How do you reverse?
kidne or liver clearance?
Eliquis. Factor Xa inhibitor
idarucizumab (praxbind)
dialysis
Pcc
liver clearance
What to do with carotid injuries depending on size?
What about very high carotid injury? How to expose
Jugular injury?
<2 cm: primary repair
>2 cm: vein patch (saphenous graft)
High: subluxate the mandible or divide the digastrics
Just ligate the veins
For ogilvie’s how much neostigmine do you give? Over how long?
2.5mg over 3 minutes
Should see effect within 10 minutes
When is resuscitative thoracotomy indicated for penetrating vs blunt traumas?
Penetrating: thoracic trauma who are hemodynamically unstable on arrival to the ED despite resuscitation
Or in patients who have been pulseless and receiving CPR for less than 15 minutes
Blunt: pts who lose vital signs in transit or in the ED + no obvious non-survivable injury
Or in patients with cardiac tamponade rapidly diagnosed by ultrasound with no obvious non-survivable injury
What are the grades of frostbite?
Grade I: superficial, numbness, firm plaque (1-2 weeks to heal)
Grade II: clear or milky blisters (2-4 wks to heal) - drain these
Grade III: bloody blisters. Black eschars (1-3 months) - may aspirate but leave intact. do not debride
Grade IV: black mummified skin. Involves bone
Medially rotated leg vs externally rotated leg. gotta watch out for injury to what structure for each scenario?
Internal rotation: posterior dislocation. Sciatic nerve
External rotation: anterior dislocation.
What makes a DPL positive?
~10mL of gross blood, bile, food
> 100,000 RBC
> 500 WBC
What are the lab value indications for damage control laparotomy for trauma?
PH < 7.2
Base deficit > 15
Temp < 35