Transport in Cells Flashcards
Diffusion
Movement of particles from an area of high concentration to an area of low concentration
Down a concentration gradient until dynamic equilibrium is reached
Passive (caused by natural kinetic energy of molecules)
Passive Transport Methods
Diffusion
Facilitated diffusion
Osmosis
Properties of Molecules that affect transport
Size of molecule
Solubility in lipids and water
Polarity (charge)
Small, non-polar (oxygen, carbon dioxide)
-Rapidly diffuse across a membrane
Small, polar (water, urea)
-Diffuse across a membrane but slower
Charged particles (Ions)
-Cannot diffuse across a membrane, no matter size
Carrier Proteins
Can switch between two shapes
Binding site can be open to one side of membrane first and then open to the other side of the membrane
Specific
Channel Proteins
Water filled pores
Fixed shape
Specific
Phospholipids
Form a bilayer (two layers of phospholipid molecules)
Hydrophobic tails (fatty acid chains) point in towards the membrane interior
Hydrophilic heads (phosphate groups) point out towards the membrane surface
form a barrier to anything which is not lipid-soluble
Cholesterol
Are absent in prokaryotes membranes
Control fluidity of a membrane
Fits between phospholipid molecules
Increases fluidity at low temperatures
Decreases fluidity at high temperatures
Glycolipids & glycoproteins
Cell recognition
Cell signalling
Receptor binding sight
Facilitated Diffusion
Active Transport
Active transport moves molecules against their gradient, from low to high concentration.
This involves a carrier protein which carries the molecule from one side of the membrane to the other.
It is an active process and uses ATP to release energy.
An example is the transport of glucose from the villi of the intestine into the bloodstream.
Cotransporters are a special type of carrier protein which can bind to two molecules at a time. The concentration gradient of one molecule is used to transport the other molecule against its gradient.
Rate of active transport depends on:
-The number of carrier proteins in the membrane
-The speed of each carrier protein
-The rate of respiration
Fluid Mosaic Model
‘fluid’ because the phospholipids are constantly moving around
‘mosaic’ because both protein and phospholipids are arranged together
Extrinsic and Intrinsic Proteins
Intrinsic:
-Span whole membrane
-Facilitated diffusion
Extrinsic:
-surface of the plasma membrane
-function as enzymes