Transplantation

Question 1

Disease states causing liver failure that may be successfully treated with transplant.

Answer 1

-Noncholestatic Cirrhosis-Alcoholic
Nonalcoholic fatty liver disease Hepatitis C
Cryptogenic cirrhosis Autoimmune cirrhosis
Hepatitis B
Drug or exposure induced

-Cholestatic Cirrhosis-
Primary biliary cirrhosis (PBC) Primary sclerosing cholangitis (PSC)
Caroli disease
Choledochol cyst

Question 2

Main Indications for adult liver transplantation

Answer 2

two main categories: (1) symptomatic liver failure or (2) hepatocellular cancer if tumor location or accompanying liver disease prevents resection.

Question 3

Most common cases of renal disease in patient for transplant waiting list

Answer 3

Diabetes
Hypertension

Question 4

Absolute contraindications for renal transplantation

Answer 4

Active malignant disease
Active infection Unreconstructable peripheral vascular disease
Severe cardiac or pulmonary disease
Active intravenous drug abuse Significant psychosocial barriers that interfere with the patient’s ability to comply with a complex medical regimen

Question 5

Relative contrandications for renal transplantation

Answer 5

Limited life expectancy
History of nonadherence to medication regimen
History of noncompliance with dialysis
Financial barriers
Psychiatric issues
Renal disease with high recurrence rate
Morbid obesity (BMI is center dependent)
Frailty