Transplant Medicine Flashcards
1
Q
Etanercept is what type of medication?
A
Etanercept is a human fusion protein of TNF-a type 2 receptor that binds to and inactivates soluble tumor necrosis factor.
2
Q
Cellcept MOA?
A
Mycophenolate mofetil (MMF, CellCept) is a prodrug of mycophenolic acid (MPA), an inhibitor of inosine-5’-monophosphate dehydrogenase. MPA depletes guanosine nucleotides preferentially in T and B lymphocytes and inhibits their proliferation, thereby suppressing cell-mediated immune responses and antibody formation.
