Transplant Flashcards
1
Q
Top 3 malignancies post transplant
A
- Squamous cell cancer of skin
- PTLD
- Basal cell cancer of skin
2
Q
Immediate allergic reactions mediated by which cytokine
A
IL-4 (causes IgE production and mast cell activation)
3
Q
Hyeracute rejection histology and immune reaction
A
endothelial damage, antibodies and complement
4
Q
Acute rejection histology and immune reaction
A
lymphocyte infiltration and necrosis; T cells
5
Q
Chronic rejection histology and immune reaction
A
Fibrosis; T cell and B cells
6
Q
Cytokine responsible for allergic reaction due to activation of eosinophils
A
IL-5
7
Q
Monoclonal antibody to CD20
A
Rituximab
8
Q
1 and 5 year graft survival for living donor kidney transplsnt
A
97% and 85%