Transplant Flashcards

1
Q

Top 3 malignancies post transplant

A
  1. Squamous cell cancer of skin
  2. PTLD
  3. Basal cell cancer of skin
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2
Q

Immediate allergic reactions mediated by which cytokine

A

IL-4 (causes IgE production and mast cell activation)

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3
Q

Hyeracute rejection histology and immune reaction

A

endothelial damage, antibodies and complement

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4
Q

Acute rejection histology and immune reaction

A

lymphocyte infiltration and necrosis; T cells

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5
Q

Chronic rejection histology and immune reaction

A

Fibrosis; T cell and B cells

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6
Q

Cytokine responsible for allergic reaction due to activation of eosinophils

A

IL-5

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7
Q

Monoclonal antibody to CD20

A

Rituximab

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8
Q

1 and 5 year graft survival for living donor kidney transplsnt

A

97% and 85%

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