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Oral Boards > Infectious Disease > Flashcards

Infectious Disease Flashcards

1
Q

Bacterial (5), viral (3), and parasitic (3) causes of infectious diarrhea (plus 5 noninfiectious)

A
  1. Campylobacter
  2. Salmonella
  3. Shigella
  4. E. Coli
  5. Rotavirus
  6. Norovirus
  7. Astrovirus
  8. Giardia
  9. Cryptosporidium
  10. Entamoeba histolytica
  11. C. diff
  12. Malapsorption
  13. Drug effects
  14. IBD
  15. Endocrine tumors
  16. Hyperthyroidism
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2
Q

Percent of C. diff infections that progress to toxic megacolon

A

3-8%

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3
Q

American College of Gastroenterology Severe C. diff classification variables

A

Any 2 of:

  1. WBC > 15k / mL
  2. Albumin < 3 g/dL
  3. Abdominal tenderness
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4
Q

American College of GAstroenterology Severe-Complicated C.diff classification variables

A

Any 1 of:

  1. Admission to ICU
  2. Hypotensive or requiring pressors
  3. Fever > 38.5 C (101.3)
  4. Ileus
  5. Mental status changes
  6. WBC > 35k / mL
  7. Lactate > 2 mmol/L
  8. End organ failure
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5
Q

Reason that IV Flagyl is useful in C.diff treatment

A

Enterohepatic circulation

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6
Q

Some (not complete) indications for colectomy for C.diff colitis

A
  1. Lactate > 5 mmol/L
  2. WBC > 50k /mL
  3. Multisystem organ failure
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7
Q

Type 1 NSTI bacteria

A

polymicrobial to include gram positive, negative, and fungal

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8
Q

Type 2 NSTI bacteria

A

monomicrobial

  1. Beta hemolytic strep
  2. clostridium perfringens
  3. Staph aureus
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9
Q

Type 3 NSTI bacteria

A

water associated - vibrio vulnificus

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10
Q

Labs to get if concerned about NSTI (LRINEC score)

A

CRP
CBC w diff
BMP (sodium, cr)
ABG

Score > 8 is very concerning.

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11
Q

Important element of surgery for NSTI in addition to debridement

A

send fluid or tissue for gram stain and culture.

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12
Q

most common cause of SBP

A

E. coli

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13
Q

C. diff toxin that causes intestinal necrosis

A

Toxin A

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14
Q

qSOFA parameters

A

Resp rate > 22
GCS < 15
SBP < 100 mm Hg

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15
Q

NHSN SSI criteria

A

within 30 days of procedure
skin or subQ tissue
Purulent drainage or bacterial growth or wound opened or clinical diagnosis by physican

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16
Q

Transmission rate of exposure to Hep c

A

0.1%, no post exposure prophylaxis recommended

17
Q

Emphasemetous cholecystitis most commonly caused by

A

Clostridia species

18
Q

Mechanism of fluconazole

A

Binds p450 on fungus 14 alpha demthylase

19
Q

Caspofungin mechanisms

A

inhibits fungal cell wall synthesis

20
Q

Amphotericin mechanism

A

binds to fungal cell walls sterols causing lysis

21
Q

Infectious cause of GI bleeding in HIV patients

A

CMV

Oral Boards (23 decks)

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