Transmission beween Neurons

Question 1

What molecule forms the Neurotransmitter stored in vesicles?

Answer 1

-Precursor-Compound forms another

Question 2

What ion influx does an Action Potential trigger?

Answer 2

• Calcium channels open

- Calcium ion influx

Question 3

What activates the release of neurotransmitter into the Synaptic Cleft?

Answer 3

-Calcium ions entry

Question 4

What happens to the neurotransmitter once bound to Post-Synaptic membrane receptors?

Answer 4

Enzyme-Mediated Inactivation of Neurotransmitter occurs (prevents constant stimulation)
Re-Uptake of Neurotransmitter and of precursor be re-used

Question 5

How many sub-units can a Nicotinic Receptor be composed of?

Answer 5

• X5-Different combinations alter receptor function

- NOT Type of Cholinergic Receptor

Question 6

What drugs can alter Cholinergic Receptor activity?

-(Includes- Muscarinic and Adrenergic

Answer 6

• Depolarisation Block-
• Competitive Antagonism-
• Non-Competitive Antagonism

Question 7

What can Muscarinic Receptors form?

Answer 7

-G-Protein Coupled Receptors

Question 8

What are Pre-Synaptic Auto receptors?

Answer 8

• Modulate release of neurotransmitters
• Located at nerve terminal of Post-Synaptic neurons
• Mediate negative feedback inhibition of neurotransmitter release associated with calcium channels and influx
• Whether neurotransmitter release continues or stops