translation Flashcards

1
Q

where does the mRNA go to?

A

moves out the nucleus via the nuclear pores
into the RER
which contains 80s ribosomes and tRNA and amino acids

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2
Q

what is the first step of translation?

A

ribosomes recognises the START codon and attaches to the mRNA covering the first two codons

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3
Q

what is the second step of translation?

A

tRNA complementary to the codons attaches to the mRNA via hydrogen bonds

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4
Q

what is the third step of translation?

A

each tRNA carries an amino acid

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5
Q

what is the fourth step of translation?

A

a peptide bond is formed between the 2 amino acid using ATP by a condensation reaction

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6
Q

what is the fifth step of translation?

A

bond between the first tRNA and the amino acid breaks

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7
Q

what is the sixth step of translation?

A

ribosome moves one codon to the right

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8
Q

what is the seventh step of translation?

A

next tRNA moves in and the process repeats

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9
Q

what is the eighth step of translation?

A

the polypeptide chain is synthesised adding one amino acid at a time

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10
Q

what is the ninth step of translation?

A

when the ribosome reaches the STOP codon, it dissociates from the mRNA

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11
Q

what is the tenth step of translation?

A

tRNA and the polypeptide chain are released

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12
Q

how does the sequence of bases on DNA determine the sequence of amino acids in a polypeptide chain?

A

order of tRNA attaching to mRNA in translation is dependent on the sequence of codons
so order of amino acids is determined by the sequence of codons which is determined by the sequence of bases/ triplet DNA

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