translation

Question 1

Goal

Answer 1

mRNA to poly peptide chain to protein

Question 2

where?

Answer 2

cytoplasm

Question 3

tRNA

Answer 3

• anticodon thats complementary and antiparallel to mRNA
• goes in 3 to 5 direction
• 3rd base is often INOSINE (wobble effect)

Question 4

Ribosome

Answer 4

• small unit attaches to mRNA
• large unit has A P and E site for tRNA

Question 5

initiation

Answer 5

• 5’ cap of mRNA binds to small ribosome unit
• rRNA moves down mRNA until start codon
• tRNA with comp. anticodon binds in P spot
• big subunit assembles to rRNA

Question 6

elongation

Answer 6

• tRNA binds at A site
• A site and P site amino acid bind tgth to start poly peptide chain at A site
• P site empty now so ribo moves one down (5 to 3)
• empty tRNA exits through E
• ribo continues to move and codes for AA chain

Question 7

termination

Answer 7

• stop codon is reached at A SITE and ribo dissasembles
• AA chain is released