Transient Ischemic Attacks / Strokes Flashcards
What is a cerebrovascular accident?
Sudden loss of function due to lack of blood flow to the brain
What are the types of strokes? (3)
- Ischemic
- Hemorrhagic
- Transient ischemic attack (TIA)
What is the most common type of stroke?
Ischemic
Describe pathophysiology of ischemic strokes (2)
- Abrupt disruption of blood flow
- Lack of oxygen / nutrients to part of the brain
What are the causes of ischemic strokes? (3)
- Embolus
- Thrombus
- Hypoperfusion
What process takes place due to disruption of blood flow?
Anaerobic respiration
Describe the pathophysiology of an ischemic cascade (3)
- Decreased efficiency of neurons
- Decreased ATP
- No cellular function
What is the penumbra region?
Ischemic brain tissue that may be salvaged with timely intervention
The penumbra region is an area of …
Cerebral blood flow surrounding the infarction
In older age, ______ are at higher risk of strokes
Women
Neurological deficits caused by strokes are dependent on what factors? (3)
- The location of affected area
- The size of affected area
- The amount of collateral blood flow surrounding affected area
What is a contralateral stroke?
The side of the body that is functionally affected is opposite to the brain hemisphere affected by the stroke
- Right-sided stoke - left side of the body is affected
- Left-sided stroke - right side of the body is affected
What are the manifestations of an ischemic stroke? (5)
- Difficulty speaking
- Loss of coordination
- Visual disturbances
- Confusion
- Weakness
Why is blood glucose testing used for stroke diagnosis?
Hypoglycemia mimics stroke - rule out
What is the primary diagnostic testing used for stroke diagnosis?
MRI
What is the purpose of a non-contrast CT scan of the head in stroke diagnosis?
Determines if the stroke is ischemic or hemorrhagic
What are the types of thrombolytic therapy? (2)
- Tissue plasminogen activator (TPA)
- Tenecteplace (TNK)
What must be determined regarding eligibility of thrombolytic therapy?
Last known well / last known normal time
Thrombolytic therapy must take place ______ after onset of symptoms
3 hours
What is endovascular therapy in the treatment of strokes?
Catheterization through an artery to retrieve a clot
Endovascular therapy is considered for EVERY patient within ______ of onset of an acute stroke
4.5 hours
Even if endovascular therapy is considered, ______ should still be administered
TPA