Transfusion Reactions Flashcards
How do you treat a patient with Acute Hemolytic Reaction?
IV Fluids + Mannitol to prevent Kidney Injury
Stop the Transfusion Immediately
Monitor for DIC with coagulation studies
How is a Delayed Hemolytic Reaction treated?
No specific treatment
May need additional transfusions
How do you treat Febrile Non-hemolytic Transfusion Reactions or Leukoagglutinin Reactions?
Acetaminophen + Benadryl
(IV Corticosteroids may also be used)
How do you treat an anaphylactic reaction due to a blood transfusion?
Stop the Transfusion Immediately
Administer Epinephrine
Glucocorticoids (if severe)
How do you treat Transfusion-Related Acute Lung Injury?
Supportive Treatment
(usually resolves without complications)
How do you treat Transfusion-Associated Circulatory Overload?
Diuretics + Inotropes
Stop the Transfusion
Supportive Care
If a mother’s Indirect Coomb’s Test is negative for antibodies against Rh factor, what should you administer?
Rhogam
When is Rhogam administered to a Rh- mother that is not producing antibodies against Rh factor?
28 Weeks
40 Weeks
(or if more than 12 weeks since last dose)
What does Rhogam do?
Destroy fetal Rh positive cells so the mother will not produce anti-Rh antibodies in the next pregnancy.
How do you manage an Rh- mother with known maternal alloimmunization (antibody against Rh factor)
Determine fetal Rh
Monitor for fetal anemia if the baby is Rh+
How do you treat a baby with Severe Fetal Anemia that is near term?
Delivery
How do you treat a baby with Severe Fetal Anemia that is remote from term?
Intrauterine Fetal Transfusions
