Bleeding Disorders

Question 1

What medication can be used to increase Factor III (8) and von Willebrand Factor in patients with Hemophilia A?

Answer 1

Desmopressin (DDAVP)

Question 2

What is the first line therapy for Hemophilia A

Answer 2

Factor VIII (8) Infusion

Question 3

What is the first line therapy for Hemophilia B

Answer 3

Factor IX (9) Infusion

Question 4

How do you treat a patient for Factor V Leiden Mutation?

Answer 4

Anticoagulation Medications
(Oral or Warfarin)

Question 5

What is the mainstay of treatment for patients with Hemophilia C (Factor XI)

Answer 5

Factor XI Replacement
Fresh Frozen Plasma if it is not available
Adjunctive Aminocaproic Acid or Tranexamic Acid

Question 6

What is the primary treatment medication for a patient with Mild to Moderate von Willebrand Disease?

Answer 6

Desmopressin

Question 7

What is the primary treatment of a patient with severe von Willebrand Disease or a patient who lacks von Willebrand Factor entirely?

Answer 7

Infusion of von Willebrand Factor-containing product

Question 8

How do you treat Heparin Induced Thrombocytopenia?

Answer 8

Stop Heparin + Start Agatroban
Order diagnostic test
Doppler all 4 extremities for thrombosis

Question 9

What is the treatment for DIC?

Answer 9

Supportive (Treat the Underlying cause)
Platelet Transfusion
Fresh Frozen Plasma
Cryoprecipitate to replace Fibrinogen