Transfusion Flashcards

1
Q

how are RBCs stored

A

at 4 degrees celcius for 35 days after collection

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2
Q

what is added to keep the RBCs healthy

A

most plasma removed and solution of electrolytes, glucose and adenine is added to keep the cells healthy

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3
Q

what is the usual transfusion time for RBCs

A

1.3-3 hours

must be transfused within 4 hours after removal from cold storage

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4
Q

how much is one unit of RBCs

A

about 275ml

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5
Q

how are platelets stored

A

at room temp (22degrees)

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6
Q

what is the shelf life of platelets

A

short - 5 days from collection

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7
Q

what is the adult therapeutic dose of platelets?

A

4 pooled donations or equivalent number from single apheresis donation

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8
Q

what is the usual transfusion time for platelets

A

30mins per unit

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9
Q

how is fresh frozen plasma stored

A

at -30degrees (frozen!!!) for up to 24 months

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10
Q

what must happen before FFP is used

A

thawed immediately before use, takes 20-30 mins

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11
Q

what is the usual transfusion time of FFP

A

30 minutes per unit

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12
Q

what is the usual dose of FFP

A

12-15ml/kg (4-6 units) for an average adult

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13
Q

what are the values to trigger RBC tranfusion

A
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14
Q

what is the threshold for RBC transfusion with chronic anaemia due to myeloid failure syndromes

A

80-100g/L Hb

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15
Q

what is the threshold for chronic anaemia due to inherited deficiency

A

90-95g/L Hb

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16
Q

what is the target for Hb in chronic anaemia due to inherited deficiency

A

100-120g/L Hb

17
Q

when would platelets be transfused for BM failure?

A
18
Q

why would platelets be transfused in severe haemorrhage?

A

to keep platelets >75x10^9/L

19
Q

what is the target for platelet transfusion in minor surgery prophylaxis

A

50x10^9/L

20
Q

target for platelet transfusion in major prophylaxis?

A

80x10^9/L

21
Q

target for platelet transfusion in CNS/ eye surgery?

A

100x10^9/L