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Boards > transcription factors > Flashcards

transcription factors Flashcards

1
Q

WNT/ B- catenin

A

WNT signals B catenin to activate osteoblasts

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2
Q

ZPA

A

regulates med/ lateral differentiation

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3
Q

Sclerostin/ Dickoff

A

inhibits WNT and osteoblasts

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4
Q

SOX9

A

In endochondral ossification, stimulates chondrocytes to produce Col 2,9, and 11, aggrecan, chondromodulin-1 and matrilin-3

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5
Q

RUNX2 and Sp7/Osterix

A

stimulates MSC to go down osteoblast line

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