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CMED 312 Ophtha module > Trans 010 Pharma Part 2 > Flashcards

Trans 010 Pharma Part 2 Flashcards

1
Q

Vasodilator for hypertension
a. Prorenin inhibitor
 A small molecule and a direct inhibitor of renin
 Administered orally and is eliminated mostly unchanged in the urine

A

Renin inhibitor

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2
Q

The first and only sulfur-containing ACE inhibitor

A

Captopril

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3
Q

A prodrug that is de-esterified in the

liver to produce enalaprilat, which inhibits ACE

A

Enalapril

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4
Q

Treatment of hypervolemic
hyponatremia and syndrome of inappropriate
ADH

A

Conivaptan

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5
Q

Antagonizes both endothelin A and B receptors and reduces pulmonary hypertension
 Also for systemic hypertension

A

Bosentan

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6
Q

are competitive inhibitors at the H1-receptor. These are lipid soluble, readily cross the blood– brain barrier, and have significant CNS actions mediated in large part by their anti-cholinergic activity.

A

H1 ANTAGONIST (ANTI-H1)

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7
Q

prevents nausea and vomiting before

surgery. Commonly used by anaesthesiologists..

A

Promethazine

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8
Q

Most common side-effect of the 1st generation drugs is; anti histamine

A

drowsiness

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9
Q

Drug of choice for Meniere’s syndrome (vertigo)  Serc / Merislon –(brandnames)

A

Betahistine

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10
Q

Used as an appetite suppressant
(anorexigenic) but was withdrawn because of cardiac valve toxicity (pulmonary HPN)
 Fibromyalgia another adverse effect

A

Dexfenfluramine

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11
Q

For ADHD in children, also a reducing pill and
narcolepsy (excessive sleeping) Can increase catecholamine, serotonin, and
glutamate release, and decrease GABA release in various brain regions

A

Modafinil

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12
Q

Treatment for serotonin syndrome

 Brand name: Periactin

A

Cyproheptadine

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13
Q

The most common precursor of the

eicosanoids

A

Arachidonic acid

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14
Q 
Adverse effect (beneficial) lengthening/growth
eyelashes
A

Bimatoprost

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15
Q

Dextromethorphan versus Butamirate Citrate

A

Dextromethorphan – central – acting
 CI: Bronchial asthma
• Butamirate Citrate (Sinecod Forte) – peripheral acting

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16
Q

Bromhexine/Ambroxol/Carbocysteine what drag class

A

mucolytic

17
Q

Guaifenasin drug class

A

Expectorant

18
Q

A mucolytic that is an antidote for poisoning, antidote for

paracetamol overdose, overdose of cyclophosphamide and watussi poisoning

A

Acetylcysteine (Poisoning)

19
Q

Safest ANALGESIC – ANTIPYRETIC

A

Paracetamol

20
Q

Aspirin is contraindicated in children because it produce

A

Reye syndrome

21
Q

Is due to anesthetic, N20,
succinylcholine – it is a dominant chromosomal abnormality in the skeletal muscle. There is an excitation in the skeletal muscle leading to contraction and hyperthermia, very high fever

A

. Malignant hyperthermia

22
Q

Treatment for

Malignant hyperthermia

A

Dantrolene

23
Q

Anti Ace reversible. For the treatment of Myasthei Gravis – disease of the skeletal muscle that affects your NMJ.

A

Carbamate

24
Q

Drug of choice for

My asthenia? For diaquosis?

A

Neostigmine is the drug of choice, edrophonium for diagnosis known as tensilon

25
Q

For cigarette smoking sensation

A

Varenicline

26
Q

The antidote for organophosphate poisioning is cholinergic

A

Atropine

27
Q

is now used for asthma, antispasmodic, is available as glycopironium bromide for treatment of emphysema.

A

Glycopyrolate

28
Q

are used for retinal exam – to prevent synechiae after surgery. Used in ophthalmology for diagnosis in the diseases of the eyes, uveitis. Infection of the choroid, iris, and ciliary body.

A

Cyclopentolate and Tropicamide

29
Q

Shortest? Shorter acting?

Long acting? Na mydriatic cyclopegic

A

The shortest acting is tropicamide, shorter acting is cyclopentolate, the long acting is homatropine, once a day, good for 24 hrs. Atropine is also 24 hours.

30
Q

is a nasal decongestant; pelvic decongestant for priapism; a drug used to localize the lesion of horner’s syndrome. Horner syndrome is due to the obstruction of the sympathetic pathway

A

Phenylephrine

31
Q

present in neozep, decolgen, causes stroke in US, in the Ph, coronary heart attack

A

Phenylpropanolamine

32
Q

treatment for orthostatic hypotension

A

Midodraine

33
Q

for htn,for post menopausal syndrome,
diabetic neuropathy and for cigarette smoking sensation din
pero di siya drug of choice for

A

Clonidine

34
Q

the drug of choice for neurogenic hypotension

A

Droxidopa

35
Q

Pwede sa asthma, pwede sa glaucoma-

A

Epinephrine

36
Q

Inhibits your phosphodiesterase 5 then increase your CGMP. For male erectile dysfunction

A

Sildenafil

37
Q

lahat ng to for glaucoma topical drug. Remember these 5

A

Metipranolol / Betaxolol Timolol / Carteolol / Levobunolol

CMED 312 Ophtha module (19 decks)

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