Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CRRAB II- Week 3 > Trachte: Gas Transport > Flashcards

Trachte: Gas Transport Flashcards

1
Q

What are the two forms that oxygen can exist in in the blood?

A

Dissolved

Associated w/ Hb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How much Oxygen is dissolved in the blood at PO2 of 100 mmHg?

A

.3 ml/dl blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What determines the amount of oxygen that is dissolved in the blood?

A

It is PROPORTIONAL to the partial pressure (.003 ml/mmHg/dL)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How much oxygen is dissolved at PO2 of 200 mmHg?

A

.6 ml

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How much oxygen is dissolved at PO2 of 50 mmHg?

A

1/2 (.3)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How much oxygen is associated w/ Hb at PO2 of 100 mmHg?

A

20 ml/dL of blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the relationship between oxygen and Hb association?

A

Sigmoidal so it is NOT direct

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How much oxygen is associated with Hb at PO2 of 40 mmHg (venous blood)?

A

15 ml/dl (75% Hb saturation)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How much oxygen is associated with Hb at 200 mm HG? At pure oxygen 760 mmHg?

A

20 ml/dl
20 ml/dl

Can’t get more than 100% saturation!!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the maximal amount of oxygen that binds to Hb?

A

1.39 ml/g

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the normal Hb level in the blood?

A

15 g/100 ml

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the maximal oxygen binding to Hb?

A

20 ml/ 100 ml of blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is oxygen saturation?

A

Amount combined w/ Hb/maximal oxygen capacity of hemoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is normal oxygen saturation for arterial blood?

A

95%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is normal oxygen saturation for venous blood?

A

75%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What affect does anemia have on hemoglobin?

A

It lowers Hb to 9 g/100 ml of blood so the O2 capacity will be redued to 13 ml O2/100 ml of blood instead of 15

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Does anemia impact PO2? Why?

A

The amount of oxygen dissolved in plasma is NOT determined by Hb so NO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Does anemia impact O2 saturation?

A

NO–this just tells you whether the RBC are saturated or not (you can have fewer there and they can still all be saturated)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Does anemia impact O2 capacity?

A

YES!

With fewer RBC you can’t deliver as much O2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

How does Hb appear when it is reduced and how does this cause cyanosis?

A

It’s purple

Hypoxia (low O2)–> reduced form–> causes cyanosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What shifts the O2 dissociation curve to the right?

A

Less affinity for oxygen

22
Q

What reduces the affinity of oxygen to Hb?

A

LOW pH
Increased CO2
Increased temprature
Increased 2,3 diphosphoglycerate

23
Q

Does CO have a greater affinity for Hb than O2? What can this do?

A

YES–> this can tie up all the Hb

240x as much

24
Q

How do you tx someone with CO poisoning?

A

Put them in a hyperbaric chamber and increase pressure by 3 atm up to 2200 mmHG to get enough O2 to dissolve in plasma.

25
Q

How id CO2 transported in the blood?

A

Dissolved
Bicarbonate
Carbamino compounds

26
Q

What percent of CO2 is transported dissolved in the blood?

A

10%

.067 x 40 = 2.67 ml CO2/dl

27
Q

What is the predominate form of CO2 in the blood?

A

Bicarbonate

25 mep/L

28
Q

What does CA do?

A

Catalyzes CO2 and water into H2CO3> H and HCO2

29
Q

What happens to bicarb and H that are made in the RBC? What happens to Cl?

A

It diffuses OUT of the RBC

H stays IN

Cl is ATTRACTED INTO the RBC

30
Q

Why is deoxygenated Hb a better carrier of CO2?

A

Acidification

31
Q

Does oxygenated or deoxygenated Hb carry CO2 better?

A

Deoxygenated

32
Q

What are carbamino compounds? This accounts for what percent of CO2 transport in the blood?

A

CO2 can bind to Hb

5%

33
Q

How does the CO2 dissociation curve differ from the O2 dissociation curve?

A

Much more LINEAR and much STEEPER

34
Q

Can the blood carry more CO2 or O2?

A

CO2

35
Q

How does O2 saturation affect the CO2 dissociation curve?

A

Shifts it to the RIGHT

36
Q

What controls bicarb levels?

A

Kidneys

37
Q

What controls PCO2 levels?

A

Lungs

38
Q

What is respiratory acidosis?

A

RETENTION of CO2

39
Q

What are typical causes of respiratory acidosis?

A

Hypoventilation

Ventilation perfusion mismatch

40
Q

What is respiratory alkalosis?

A

excessive EXHALATION of CO2

41
Q

What causes respiratory alkalosis?

A

Exposure to high altitude

42
Q

What is metabolic acidosis?

A

Decreased bicarb

43
Q

What causes metabolic acidosis?

A

Acid in blood (diabetes mellitus)

44
Q

What is metabolic alkalosis?

A

Increased concentration of bicarb

45
Q

What causes metabolic alkalosis?

A

vomiting

46
Q

How does O2 diffuse into the tissues?

A

From CAPILLARIES

47
Q

What are diffusion distances in skeletal muscle?

A

100 u

48
Q

What is the PO2 of muscle?

A

LOW 1-3 mmHg

49
Q

What helps to keep the PO2 in muscle uniform?

A

myoglobin

50
Q

What cause hypoxia/ decreased O2 delivery?

A

Low arterial PO2
Anemia
Tissue blood flow disruption (embolism, thrombus)
Poison

CRRAB II- Week 3 (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions