Toxoplasmosis. Flashcards

1
Q

(P) Def de Toxopaslmsosi

A

-Infeccion parasitaria intracelula por T gondii.

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2
Q

(P)Epidemio de la Toxo

A
  • 1/3 pobl esta infectada cronicamente
  • 5-1000 Embarazadas con sist inmune competnte.
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3
Q

(P)Forma de Transmision de la Toxo:

A
  • Bradizoitos: VO (Tambien los ooquistes), organos transplantados.
  • Ooquistes
  • Taquizoitos: trasnfusion de samgre, placenta.
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4
Q

(P)Ciclo vital del toxo

A
  • fase no felina o asexual
  • Fase felina o sexual
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5
Q

(P)En que porcentaje seran asinomaticos

A

90%

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6
Q

(P) Cuales son los tipos de Toxoplasmosis son4

A
  • Congenita
  • Ganglionar
  • Ocular
  • pacientes inunodepres
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7
Q

(P)Tétrada de Sabin (Toxo congenita):

A
  • Coriorretinitis
  • Calcificaciones cerevrales difusa.
  • Convulsiones
  • Hidrocefalia.=RETRASO MENTAL
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8
Q

(p)▀ Clinico de la Toxo ganglionar:

A
  • Adenopatías (Cervical, supraclavicular, axilar y la inguinal)
  • Malestar gral
  • Se autolimita
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9
Q

(P)Toxoplasmossi ocular

A

–Coriorretinits, vision borrosa

  • Escotomas, fotofobia, d. ocular
  • Afectacion macular con perdida de la vision central.
  • NISTAGMUS Y EL ESTRABISMO.
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10
Q

(p) ▀ Clinico de los pacientes inmunodeprimidos:

A

-Adenopatias cervicales es mas frecuente

-20-40% TIENE CEFAEA, MALESTAR GRAL, FATIGA Y FIEBRE.

-VIH: Principal Infeccion oportunista para SNC

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11
Q

(P)Dx para Toxo

A
  • IgM y la IgG
  • TAC craneo.
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12
Q

(P)Tx para Toxo

A

–RNC con infeccion congenita;

Pirimetamina VO 0,5-1mg/kg O sulfadiazina 100mg/kg x d durante un año.

-los que no estan inmunodrepes y que tiene linfadenopatia no necesitan Tx.

-tx Profialctico en VIh, con <100 CD4 = Pririmetamina 50-75mg sulfadiazina y 2-5g al d

Alternativo TMP7SMX

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