Toxin/Antidote Flashcards

Given toxin, what is the antidote

1
Q

Theophylline

A

Beta-blocker

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2
Q

tPA, streptokinase, urokinase

A

Aminocaproic acid

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3
Q

warfarin

A

Vit K, fresh frozen plasma

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4
Q

heparin

A

protamine

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5
Q

TCAs

A

NaHCO3 (plasma alkalinization)

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6
Q

benzodiazepines

A

flumazenil

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7
Q

opioids

A

naloxone/naltrexone

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8
Q

methanol, ethylene glycol (antifreeze)

A

fomepizole > ethanol, dialysis

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9
Q

Carbon monoxide

A

100% O2, hyperbaric O2

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10
Q

methemoglobin

A

Methylene blue, vitamin C

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11
Q

cyanide

A

nitrite, hydroxocobalamin, thiosulfate

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12
Q

copper, arsenic, gold

A

penicillamine

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13
Q

mercury, arsenic, gold

A

dimercaprol (BAL), succimer

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14
Q

lead

A

CaEDTA, dimercaprol, succimer, penicillamine

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15
Q

iron

A

deferoxamine

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16
Q

digitalis

A

Stop dig; normalize K+, lidocaine, Anti-dig Fab fragments, Mg2+ (KLAM)

17
Q

beta-blockers

A

glucagon

18
Q

antimuscarinic, anticholinergic agents

A

physostigmine salicylate

19
Q

acetylcholinesterase inhibitors, organophosphates

A

atropine + pralidoxime

20
Q

amphetamines (basic)

A

NH4Cl (acidify urine)

21
Q

salicylates

A

NaHCO3 (alkalinize urine), dialysis

22
Q

acetaminophen

A

N-acetylcysteine (replenishes glutathione)