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FA Rapid Review > Drug Reactions > Flashcards

Drug Reactions Flashcards

Given drug reaction, what is the causal agent

1
Q

coronary vasospasm

A

cocaine, sumatriptan

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2
Q

cutaneous flushing

A

VANC: Vancomycin, Adenosine, Niacin, Ca channel blockers

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3
Q

dilated cardiomyopathy

A

Doxorubicin, daunorubicin

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4
Q

torsades de pointes

A

Class III (sotalol), class IA (quinidine) antiarrhythmics

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5
Q

agranulocytosis

A

Clozapine, Carbamazepine, Colchicine, PTU, Methimazole, Dapsone
(Agranulocytosis Could Certainly Cause Pretty Major Damage)

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6
Q

aplastic anemia

A

chloramphenicol, benzene, NSAIDs, PTU, methimazole

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7
Q

direct Coombs-positive hemolytic anemia

A

methyldopa

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8
Q

gray baby syndrome

A

chloramphenicol

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9
Q

hemolysis in G6PD-deficient pts

A

Isoniazid (INH), sulfonamides, primaquine, aspirin, ibuprofen, nitrofurantoin
(Hemolysis IS PAIN)

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10
Q

megaloblastic anemia

A

phenytoin, methotrexate, sulfa drugs

have a blast with PMS

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11
Q

thrombotic complications

A

OCPs

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12
Q

cough

A

ACE-I

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13
Q

pulmonary fibrosis

A

BLeomycin, Amiodarone, Busulfan

it’s hard to BLAB when you have pulm fibrosis

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14
Q

acute cholestatic hepatitis

A

erythromycin

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15
Q

focal to massive hepatic necrosis

A

halothane, acetaminophen, valproic acid, Aamanita phalloides

liver HAVAc

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16
Q

hepatitis

A

INH

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17
Q

pseudomembranous colitis

A

clindamycin, ampicillin

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18
Q

adrenocortical insufficiency

A

glucocorticoid withdrawal (HPA suppression)

19
Q

gynecomastia

A

Spironolactone, Digitalis, Cimetidine, chronic Alcohol use, estrogens, Ketoconazole
(Some Drugs Create Awesome Knockers)

20
Q

hot flashes

A

tamoxifen, clomiphene

21
Q

hypothyroidism

A

lithium, amiodarone, sulfonamides

22
Q

hyperglycemia

A

niacin, tacrolimus, protease inhibitors

23
Q

fat redistribution

A

glucocorticoids, protease inhibitors

24
Q

gingival hyperplasia

A

phenytoin, verapamil

25
Q

gout

A

furosemide, thiazides, niacin, cyclosporine, pyrazinamide

26
Q

myopathies

A

Fibrates, Niacin, Colchicine, Hydroxychloroquine, Interferon alpha, Penicillamine, Statins, Glucocorticoids
(Fish N CHIPS Give you myopathies)

27
Q

osteoporosis

A

corticosteroids, heparin

28
Q

photosensitivity

A

Sulfonadmides, Amiodarone, Tetracycline

SAT for a photo

29
Q

rash (Stevens-Johnson syndrome)

A

Penicillin, Ethosuximide, Carbamazepine, Sulfa drugs, Lamotrigene, Allopurinol, Phenytoin, Phenobarbital
(bad rash after a PEC SLAPP)

30
Q

SLE-like syndrome

A

hydralazine, INH, procainamide, phenytoin

31
Q

tendonitis, tendon rupture, cartilage damage (kids)

A

fluoroquinolones

32
Q

diabetes insipidus

A

lithium, demeclocycline

33
Q

fanconi’s syndrome

A

expired tetracycline

34
Q

interstitial nephritis

A

methicillin, NSAIDs, furosemide

35
Q

hemorrhagic cystitis

A

cyclophosphamide, ifosfamide (prevent by coadministering with mesna)

36
Q

SIADH

A

carbamazepine, cyclophosphamide

37
Q

cinchonism (overdose)

A

quinidine, quinine

38
Q

parkinson-like syndrome

A

antipsychotics, reserpine, metoclopramide

39
Q

seizures

A

bupropion, imipenem/cilastatin, isoniazid

40
Q

tardive dyskinesia

A

antipsychotics

41
Q

antimuscarinic

A

atropine, TCAs, H1 blockers, neuroleptics

42
Q

disulfiram-like reaction

A

metronidazole, certain cephalosporins, procarbazine, 1st generation sulfonylureas

43
Q

nephrotoxicity/ototoxicity

A

aminoglycosides, vancomycin, loop diuretics, cisplatin

FA Rapid Review (11 decks)

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