toxin Flashcards

1
Q

lead toxicity

A

5-44 Nothing
45-69 = 2,3 dimercaptosuccinic acid (DMSA , succimer) with the side effecy of rash and neutopeniaa

sever more than 70 = dimercaprol plus calcium disodium edetate( EDTA)

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2
Q

ginko bilboba

A

memory enhancement

increased bleeding

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3
Q

ginsing

A

improved mental performance

increased bleeding

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4
Q

saw palmetto

A

benign prostatic hyperplasia

mild stomach discomfort

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5
Q

black cohosh

A

menoposal symptomes( hot flashes and vaginal dryness)

hepatic injury

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6
Q

st johns wort

A

depression insomnia

drug intaction : antidepressant ( serotonin synd)
OCs( oral conta..)
anticogulant( decreases the INR)
digoxin

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7
Q

kava

A

anxiety and insomnia

sever liver damage

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8
Q

licorice

A

stomach ulcers , bronchitis

hypertension and hypokalemia

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9
Q

echinacea

A

treatment and prevention of cold and flu

allergic reaction , dyspepsia

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10
Q

ephedra

A

treatment if cold and weight loss

HTN arrhythmia, MI, sudden death , stroke, seizure

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11
Q

scombroid poisening

A

spicy fish , flushing, throbing headacem palpitations, and abdominal
cramps , diarrhea , oral burning

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12
Q

inducers

A

chronic alcoholsim, barbituates, carbamazepin, grisiofulvin, modafinil, pjenytoin, rifampin, st johns wort

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13
Q

inhibitors

A

acute alcoholisim, amiodarone, azoles, cimethidine, diltiazim and verapamil, grapefruit juice, izoniazides, macrolides, quinolones, protease inhibitors ( ritonavir) ,SSRI

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14
Q

riluzole

A

glutamate inhibitor prolong survaival andd delay the need for tracheostomy

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15
Q

gerstman synd

A

dominanat parital , difficulty performing simple arthmetic tast ( acalculia) , inability to name individual fingers, ( finger afnosia) , impaired writing(agraphia) , right and left confusion

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16
Q

copying simple act , line drwang, wearing clothes. dressing apraxia,

A

nondominant parietal ( right side)

17
Q

wernike

A

dominant temporal

18
Q

temporal (both sides )

A

homonymous upper quadrantanopia)

19
Q

3 hz spike and wave discharge

A

absence epilepsy

21
Q

tuberous sclerosis ( if you can read t in the book)

A

AD,
derm: ash leaf spot, angiofiromas, shagreen patches,
neurologic; CNS lesions, (subemendymal tumors,) epilepsy, intellectual disability, autisim,
cardiovascular; rhabdomyomas,
renal ; angiomyolipomas

22
Q

disease modifying drugs for MS

A

beta interfrone, glatiramer

23
Q

tizanidine

A

muscle relaxant

24
Q

valproic acid side effects

A

thrombocytopenia, and other cells,, hepatotoxicity, and panreatitis, and its teratogen

25
tissue plasminogen antidote
cryoprecipitate
26
dabigatran antidote
Idarucizumab
27
manifestations of sarcoidosis
pulmonary: bilateral hilar adenopathy , iterstitial infiltrates cutaneous; popular , nodular, or plaquelike lesions, erythema nodosum, ophtalmologic: anterio and posterior uveitis, keratoconjictivitis, reticuloendothelial, : peripheral lymphadenopathy, hepatosplenomegaly, musculoskeletal; acute polyarthritis, chronic arthritis, cardiovascular ; atrioventricular block, dilated restrictive cardiomegaly CNS and endocrine; facial nerve palsy, central DI, hypercalcemia lofgern synd; erythema nodosum, hilar adenopathy, migratory polyarthralgia, fever
28
fronto temporal dementia
tau protein inclusions ( pick body) 50-6- hyperorality apathy and ritialistic, behavioral ... , empathy losss
29
wernicke encephalopaty 3 items
encephalopathy : disorientation, oculomotor dysfunction ; lateral rectuss palsy gait ataxia; wide based gaitkor
30
korsakof synd
retrograde and anterograde amnesia and confabulation, social behaivor and long term memory loss, ; mammillary body atrophy
31
cerebral palsy MRI
periventricular leukomalacia basal gangllia lesions
32
two item check before thrombolysis
BP under 180 and start the antipletlet after 24 hours, avoid hypotention
33
what kind of hematoma in chldren needs CT scan
nonfrontal hematoma
34
large vessel oclusion
24 h mechanical thrombectoy
35