toxin Flashcards
lead toxicity
5-44 Nothing
45-69 = 2,3 dimercaptosuccinic acid (DMSA , succimer) with the side effecy of rash and neutopeniaa
sever more than 70 = dimercaprol plus calcium disodium edetate( EDTA)
ginko bilboba
memory enhancement
increased bleeding
ginsing
improved mental performance
increased bleeding
saw palmetto
benign prostatic hyperplasia
mild stomach discomfort
black cohosh
menoposal symptomes( hot flashes and vaginal dryness)
hepatic injury
st johns wort
depression insomnia
drug intaction : antidepressant ( serotonin synd)
OCs( oral conta..)
anticogulant( decreases the INR)
digoxin
kava
anxiety and insomnia
sever liver damage
licorice
stomach ulcers , bronchitis
hypertension and hypokalemia
echinacea
treatment and prevention of cold and flu
allergic reaction , dyspepsia
ephedra
treatment if cold and weight loss
HTN arrhythmia, MI, sudden death , stroke, seizure
scombroid poisening
spicy fish , flushing, throbing headacem palpitations, and abdominal
cramps , diarrhea , oral burning
inducers
chronic alcoholsim, barbituates, carbamazepin, grisiofulvin, modafinil, pjenytoin, rifampin, st johns wort
inhibitors
acute alcoholisim, amiodarone, azoles, cimethidine, diltiazim and verapamil, grapefruit juice, izoniazides, macrolides, quinolones, protease inhibitors ( ritonavir) ,SSRI
riluzole
glutamate inhibitor prolong survaival andd delay the need for tracheostomy
gerstman synd
dominanat parital , difficulty performing simple arthmetic tast ( acalculia) , inability to name individual fingers, ( finger afnosia) , impaired writing(agraphia) , right and left confusion
copying simple act , line drwang, wearing clothes. dressing apraxia,
nondominant parietal ( right side)
wernike
dominant temporal
temporal (both sides )
homonymous upper quadrantanopia)
3 hz spike and wave discharge
absence epilepsy
tuberous sclerosis ( if you can read t in the book)
AD,
derm: ash leaf spot, angiofiromas, shagreen patches,
neurologic; CNS lesions, (subemendymal tumors,) epilepsy, intellectual disability, autisim,
cardiovascular; rhabdomyomas,
renal ; angiomyolipomas
disease modifying drugs for MS
beta interfrone, glatiramer
tizanidine
muscle relaxant
valproic acid side effects
thrombocytopenia, and other cells,, hepatotoxicity, and panreatitis, and its teratogen
tissue plasminogen antidote
cryoprecipitate
dabigatran antidote
Idarucizumab
manifestations of sarcoidosis
pulmonary: bilateral hilar adenopathy , iterstitial infiltrates
cutaneous; popular , nodular, or plaquelike lesions, erythema nodosum,
ophtalmologic: anterio and posterior uveitis, keratoconjictivitis,
reticuloendothelial, : peripheral lymphadenopathy, hepatosplenomegaly,
musculoskeletal; acute polyarthritis, chronic arthritis,
cardiovascular ; atrioventricular block, dilated restrictive cardiomegaly
CNS and endocrine; facial nerve palsy, central DI, hypercalcemia
lofgern synd; erythema nodosum, hilar adenopathy, migratory polyarthralgia, fever
fronto temporal dementia
tau protein inclusions ( pick body)
50-6-
hyperorality apathy and ritialistic, behavioral … , empathy losss
wernicke encephalopaty 3 items
encephalopathy : disorientation,
oculomotor dysfunction ; lateral rectuss palsy
gait ataxia; wide based gaitkor
korsakof synd
retrograde and anterograde amnesia and confabulation, social behaivor and long term memory loss, ; mammillary body atrophy
cerebral palsy MRI
periventricular leukomalacia basal gangllia lesions
two item check before thrombolysis
BP under 180 and start the antipletlet after 24 hours, avoid hypotention
what kind of hematoma in chldren needs CT scan
nonfrontal hematoma
large vessel oclusion
24 h mechanical thrombectoy
