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Pharmacology > Toxicology > Flashcards

Toxicology Flashcards

1
Q

What are the three classifications for toxic reactions? What do each cause?

A

Pharmacological - reversible
Pathological - tissue damage
Genotoxic - long term effects in genetic components

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2
Q

What are 5 ways to prevent absorption?

A 
Emesis
Gastric Lavage
Whole bowel irrigation
Chemical absorption
Cathartics (decrease in small intestine)
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3
Q

What are 4 ways to enhance elimination?

A

Urinary excretion
Multidose-activated charcoal
Altered metabolism
Dialysis

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4
Q

What is the primary source for arsenic? What is the average daily intake?

A

Drinking water

10ug/day

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5
Q

Which heavy metal displaces calcium and zinc in proteins?

A

Lead

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6
Q

Which two heavy metals target the CNS?

A

Lead and Mercury

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7
Q

What does dimercaprol and EDTA treat?

A

lead and mercury

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8
Q

What does penicillamine treat?

A

Copper

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9
Q

What does defroxamine bind avidly to?

A

Iron

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Pharmacology (7 decks)

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