Antimicrobials - NAI and FSI

Question 1

What should the dose for bactrim (sulfamethoxazole/trimethoprin) be based on?

Answer 1

Creatine Clearance

Question 2

What is the only drug combo that inhibits folate synthesis? What is another name for it?

Answer 2

Sulfamethoxazole/Trimethoprin

Bactrim

Question 3

What is the MOA of metronidazole?

Answer 3

Nucleic Acid Inhibitor

Question 4

Which fluroquinolines cna treat S. Pneumoniae? Which cannot?

Answer 4

Can - Moxi/Levo

Can’t - Cipro

Question 5

What is the main ADR to fluroquinolines?

Answer 5

QTc prolongation

Question 6

What should not be consumed while taking fluroquinolines? Which protein synthesis inhibitor family has the same consumption restriction?

Answer 6

Divalent or trivalent cations

Tetracyclines

Question 7

What two substances does metronidazole have drug/drug interactions with?

Answer 7

Warfarin and ethanol

Question 8

Which fluroquinolines can treat P. aeruginosa? Which cannot?

Answer 8

Can - Cipro/Levo

Can’t - Moxi

Question 9

What is the MOA of fluroquinolines?

Answer 9

Nucleic Acid Inhibitor

Question 10

What is the general spectrum for moxifloxacin, ciprofloxacin, and levofloxacin?

Answer 10

G+, atypical bacteria

Question 11

What two illnesses does bactrim work against?

Answer 11

UTI

Question 12

What family and single organism does metronidazole cover?

Answer 12

Anerobes and C. Diff

Question 13

What are three fluroquinolines?

Answer 13

Moxifloxacin
Ciprofloxacin
Levofloxacin