Toxicology Flashcards
What is the therapeutic index equations?
The lethal dose devided by the effective dose.
The larger the number, the safer the drug.
Whats the use of the drug naloxone?
This is for narcotic overdose.
Also known as “Narcan”
What is the use of apomorphine?
This drug makes you throw up!
Should not be used if the person has absorbed petroleum hydrocarbon solvent or in the presence of caustic acid or alkali agent.
What is the use of the drug pralidoxime?
2-PAM
It is used to reverse insectiside poisoning, tabum, etc.
Usually used with atropine to block excessive muscarinic responses.
What are the cures for cyanide poisoning?
You will use nitrites.
Think inhaled amyl nitrite and intravenous sodium nitrite or sodium thiosulfate.
What is the use of the drug DMSA (Succimer)?
This is used for lead poisoning.
Remember that it is a very long term treatment, and that it is difficult to adhere to.
What is the use of the drug fomepizole?
Fomepizole blocks alcohol dehydrogenase and is considered the drug of choice for antidotal therapy for ethylene glycol or methanol toxicity.
What are Naloxone and Naltrexone used for?
these are both for the reversal of opioids.
What is the the use of the drug methylene blue?
Most commonly use to treat methemoglobinemia.
What is the use of the drug n-Acetylcysteine?
This drug is used to restore glutathione following acetometaphine overdose.
What hapens following dioxin poisoning?
This is the poison that curdles your skin!