toxico Flashcards

1
Q

syndrome anticholinergique

A

Red as a beet
Hot as a hare
blind as a bat (mydriase)
mad as a hatter (confused)
full as a flask (rétention urinaire)
tachycardie
shaking, grabbing invisible objects

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2
Q

agents anticholinergiques

A

antihistaminiques
antiparkinsoniens
antipsychotiques
antidépresseurs

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3
Q

syndrome cholinergique sx

A

SLUDGE BBB (contraire anticholinergique)
- salivation
- lacrimation
urination
defecation
emesis
bronchorrée
bronchospasme
bradycardie

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4
Q

agents causatifs anticholinergiques

A

inh acetylcholinesterase (donepezil, neostygmine)
insecricides
malathion

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5
Q

syndrome sérotoninergique

A

hyperthermie
mydriase
agitation
tachycardie
diarrhée
hypertension
clonus, hyperréflexie

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6
Q

syndrome sérotoninergique agents causatifs

A

ISRS
IRSN
IMAO
sympathomimétiques
mépéridine
dextromethorphan
millepertuis

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7
Q

syndrome sympathomimétique symptomes

A

mydiase
diaphorèse
tachycardie
tachypnée
hyperthermie
increased bowel sounds

diff avec ACh: dry skin, decreased bowel sounds

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8
Q

agents en cause syndrome sympathomimétique

A

amphétamine
cocaine
caféine
pseudo/éphédrine
LSD
méthylphénidate
PCP
théophylline

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9
Q

syndrome opioide symptomes

A

bradycardie
miosis
apnée
hypotension
hypothermie
coma

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10
Q

dextromethorphan cause

A

syndrome opioide
syndrome sérotoninergique

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11
Q

Bilans laboratoire intox

A

bio de base (FSC, Cr, é, hepatique)
gaz
substance dosable dans le sang
dépistage de médicaments ou drogues d’abus

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12
Q

CAT selon dosage de lithium

A

plus de 5: dialyse
plus de 4 avec IR: dialyse
si on anticipe que Li plus de 1 après 36h de prise en charge: dialyse

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13
Q

sirop ipeca risques

A

pas de bénéfce retardé
aspiration
AEC
retarder administration charbon de bois
CI: corrosifs, moussants, hydrocarbures, pro-convulsivants

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14
Q

Lavage gastrique indication

A

ingestion mortelle ds l’heure précédente

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15
Q

CBA inefficace si:

A

K
hydrocarbures
métaux : Fe, lithium, Pb
alcools toxiques: methanol, ethylene glycol, isopropanol

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16
Q

CI CBA

A

AEC, voies aériennes non-protégées, occlusion, iléus

17
Q

CBA multidose

A

dose q4-6h pour réduire absorption résiduelle ou encore substances causant concrétions

18
Q

Lavage intestinal

A

Polyethylene glycol
20mL/kg/h
si peu absorbé par CBA
formulations à libération prolongée (BB, BCC, Li, Fe)
tardif
mules

19
Q

CBA multidose administration recommandée

A

tricycliques
aspirine
aminophylline
carbamazepine
digitale

20
Q

comment éviter neurotoxicité aspirine

A

augmenter le pH sanguin
augmenter pH urinaire
donner bics

21
Q

antidote spécifique tylenol

A

NAC

22
Q

antidote spécifique antiCh

A

physostigmine

23
Q

antidote spécifique benzodiazépines

A

flumazénil

24
Q

antidote spécifique BB

A

glucagon
insuline
glucose

25
Q

antidote spécifique BCC

A

calcium
insuline
glucose

26
Q

antidote spécifique éthanol

A

fomépizole
éthanol

27
Q
A