Toxicities and Side Effects Flashcards

1
Q

arsenic

A

dimercaprol

succimer

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2
Q

benzo

A

flumazenil

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3
Q

b blocker

A

atropine, glucagon, saline

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4
Q

carbon monoxide

A

02

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5
Q

copper

A

penicillamine

trientine

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6
Q

cyaniide

A

nitrate +thiosulfate

hydroxycobalamine

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7
Q

digitalis (digoxin)

A

anti-dig Fab Fragments

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8
Q

gold

A

penicillamine

dimercarpol

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9
Q

herparin

A

protamine sulfate

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10
Q

iron

A

deferoxamine
deferasirox
deferiprone

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11
Q

lead

A

EDTa
dimercaprol
Succimer
Penicillamine

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12
Q

mercury

A

Dimercaprol

Succimer

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13
Q

Methanol and Ethylene Glycol

A

Fomepizole

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14
Q

Methemoglobin

A

methylene blue

vitamin C

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15
Q

opioids

A

naloxone

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16
Q

Salicylates

A

NaHCO3

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17
Q

TCA

A

NaHCO3

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18
Q

Warfarin

A

Vitamin K

Fresh Frozen Plasma

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19
Q

cause coronary vasospasm

A

Cocaine
Ergot Alkaloids
Sumatriptan

20
Q

Cause cutaneous flushing

A
Vancomycin
Adenosine
Niacin
Calcium channel blockers
Echinocandines
21
Q

Cause Dilated Cardiomyopathy

A

Doxorubicin

Daunorubicin

22
Q

how to prevent doxorubicin and daunorubicin from causing dilated cardiomyopathy

A

dexrazoxane

23
Q

cause torsades de pointes

A
AntiArryhtmics (1a and III)
AntiBiotics (Macrolides)
AntipsyChotics (Haloperidol)
AntiDepressants (TCAS)
AntiEmetics (ondansetron)
24
Q

two drugs that cause hot flashes

A

tamoxifen

clomiphene

25
Q

three drugs that cause hypothyroidism

A

lithium
amiodarone
sulfonamides

26
Q

cause acute cholestatic hepatitis and jaundice

A

erythromycin

27
Q

cause focal to massive hepatic necrosis

A

Halothane
Amanita Phalloides (death cap)
Valproic Acid
Acetaminophen

HAVAc

28
Q

drugs causing pancreatitis

A
Didanosine
Corticosteroids
Alcohol
Valproic Acid
Azathioprine
Diuretics 

Drugs causing a violent abdominal distress

29
Q

drugs causing aplastic anemia

A
Carbamazepine
methimazole
NSAIDS
Benzene
Chloramphenicol 
PPU 

Cant Make New Blood Cells Properly

30
Q

drugs causing hemolysis in G6PD

A
isoniazid
sulfonamides
dapsone
primaquine
aspirin
ibuprofen
nitrofurantoin 

Hemolysis IS D PAIN

31
Q

drugs causing megaloblastic anemia

A

Phenytoin
methotrexate
Sulfa drugs

32
Q

drugs that cause agranulocytosis

A
Clozapine
Carbamazepine
PPU
Methimazole
Colchicine
Ganciclovir 

Can Cause Pretty Major Collapse of Granulocytes

33
Q

drugs that cause fat redistribution

A

Protease Inhibitors
Glucocorticoids

FAT PIG

34
Q

drugs that cause gingival hyperplasia

A

Ca Channel Blockers
Phenytoin
Cyclosporine

35
Q

Drugs that cause hyperuricemia

A
Pyrazinamide
Thiazides
Furosemide
Niacin
Cyclosporine

Painful Tophi and Feet Need Care

36
Q

drugs that cause stephen Johnson Syndrome

A

Lamotrigine
Allopurinol
Sulfa Drugs
penicillin

37
Q

drugs that cause tendonitis or tendon rupture

A

fluoroquinolones

38
Q

drugs that cause parkinson like syndrome

A

Antipsychotics
reserpine
Metoclopramide

39
Q

drugs that cause diabetes insipudis

A

lithium

demeclocycline

40
Q

drugs that cause SIADH

A

SSRI
Carbamezpein
Cyclophosphamide

41
Q

nephrotoxic/ototoxic drugs

A

Amino glycosides
vancomycin
loops
cisplatin

42
Q

disulfiram like run drugs

A

metronidazole
cephalosporins
griseofulvin
procarbazine

43
Q

Inducers of P450

A
Chronic alcohol
St.Johns wart
Phenytoin
Phenobarbital
Nevirapine
Rifampin
Griseofulvin
Carbamazepine 

Chronic Alcoholics Steal Phen Phen and Never Refuse Greasy Carbs

44
Q

Inhibitors P450

A
Acute Alcohol Abuse
Ritonavir
Amiodarone
Cimetidine
Ketoconazole
Sulfonamides
INH
Grapefruit Juice
Quinidine
Macrolide's (Azithromycin) 

AAA RACKS IN GQ Magezine

45
Q

Sulfa Drugs

A
Sulfonamide
Sulfasalazine
Probenecid
Furosemide
Acetazolamide
Celecoxib
Thiazides
Sulfonyureas 

Scary Sulfa Pharm FACTS