Psychiatric Pharmacology

Question 1

Amitriptylline, nortriptyline, imipramine, desipramine, clomipramine, doxepin, amoxapine

Mechanism of Action
Clinical Use
Adverse Affects

Answer 1

1. -Block the reputake of Ne and Serotoin
   - block fast sodium channels
   - block muscarinic receptors
   - block alpha one receptors
   - block histamine one receptors

2. Major depression
Ocd
Neuropathic pain in diabetics
Migraine prophylaxis 
Insomnia 

3. Insomnia
Arrhythmia
Constipation, urinary retention, confusion
Sedation
Orthostatic hypotension