Cardiovascular System Flashcards
1
Q
drugs used for HTN in pregnancy
A
hydrazine
nifedipine
methyldopa
labetolol
2
Q
calcium channel blocker used for subarachnoid hemorrhage to decrease vasospasm
A
nimodipine
3
Q
ca blocker used fro HTN emergency and urgency
A
Clevidipine
4
Q
Hydrazine
MOA
USE
UDE
A
- vasodilator arterioles more then veins. increases cGMP
- severe HTN
- Lupus like symptoms
5
Q
Nitroprusside
MOA
USE
UDE
A
- short acting increases in cGMP and release of NO
- HTN emergency
- cyanide toxicity
6
Q
Fenoldapam
MOA
USE
UDE
A
D1 agonist, vasodilation. decrease in BP and increases in naturesis
- post op use for antiHTN
- hypotension
7
Q
drug of choice for malignant HTN
A
nitroprusside
8
Q
Nitroglycerin, Isosorbie di/mono nitrate
MOA
USE
UDE
A
- vasodilator by increasing NO (dilates veins more)
- Angina and Pulmonary Edema
- Monday Diseases (loss of tolerance to the vasodilation effect over the weekend)
9
Q
Ranolazine
MOA
USE
UDE
A
- inhibits the late phase of sodium current reducing diastolic wall tension
- angina
- QT prolongation
10
Q
Statins
MOA
USE
UDE
A
- inhibit conversion of HMG-CoA to mevalonate. decreases LDL
- lipids
- hepatotoxic
11
Q
Cholestryramine
Colestipol
Colesnvelam
MOA
USE
UDE
A
- prevent intestinal reasobrption of bile acid. deceases LDL
- lipid
- GI upset
12
Q
Ezetimibe
MOA
USE
UDE
A
- prevent absortion in the small intesinte (decreases LDL)
- lipid
- diarrhes
13
Q
Gemifibrozil, Bezafibrate, Fenofibrate
MOA
USE
UDE
A
- activate PPAR alpha to induce HDL synthesis and increases TG clearance
- lipid
- myopathy and gall stones
14
Q
Niacin
MOA
USE
UDE
A
- inhibits lipolysis (HSL) and reduces VLDL synthesis
- lipid
- flushed, hyperglycemia, hyperuricemia
15
Q
Digoxin
MOA
USE
UDE
A
- inhibition of sodium potassium atpase and blocks sodium calcium pump so calcium remains inside and causes contraction of the heart
- HF
- hyperkalemia
