Toxicities and side effects Flashcards by Ahmad Saqr | Brainscape

Q

What is the treatment for the following toxin:

Acetaminophen

what’s its MOA

A

N-acetylcysteine

MOA: (replenishes glutathione)

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Q

What is the treatment for the following toxin:

AChE inhibitors, organophosphates

A

Atropine followed by

pralidoxime (2-PAM)

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Q

What is the treatment for the following toxin:

Amphetamines (basic)

A

NH₄Cl (acidify the urine)

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Q

What is the treatment for the following toxin:

Antimuscarinic, anticholinergic agents

Why do we use the treatment?

A

Physostigmine salicylate

(control hyperthermia)

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Q

What is the treatment for the following toxin:

Benzodiazepines

A

Flumazenil

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Q

What is the treatment for the following toxin:

B-blockers

A

Glucagon

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Q

What is the treatment for the following toxin:

Carbon monoxide

A

100% O₂, hyberbaric O₂

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Q

What is the treatment for the following toxin:

Copper, arsenic gold

A

Penicillamine

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Q

What is the treatment for the following toxin:

Cyanide

A

Nitrite + thiosulfate, hydroxocobalamin

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Q

What is the treatment for the following toxin:

Digitalis

A

Anti-dig Fab fragments

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Q

What is the treatment for the following toxin:

Heparin

A

Protamine sulfate

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Q

What is the treatment for the following toxin:

Iron

A

Deferoxamine, deferasirox

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Q

What is the treatment for the following toxin:

Lead

A

penicillamine, EDTA, dimercaprol, succimer

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Q

What is the treatment for the following toxin:

Mercury, arsenic, gold

A

Dimercaprol (BAL)

succimer

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Q

What is the treatment for the following toxin:

Methanol, ethylene glycol (antifreeze)

A

Fomepizole>ethanol, dialysis

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Q

What is the treatment for the following toxin:

Methemoglobin

A

Methylene blue

vitamin C

Q

What is the treatment for the following toxin:

Opioids

A

Naloxone

Q

What is the treatment for the following toxin:

Heparin induced thrombocytopenia

A

Argatroban

Q

What is the treatment for the following toxin:

Salicylates

A

NaHCO3 (alkalinize urine)

dialysis

Q

What is the treatment for the following toxin:

TCAs

A

NaHCOs (plasma alkalinization)

Q

What is the treatment for the following toxin:

tPAs, streptokinase, urokinase

A

Aminocaproic acid

Q

What is the treatment for the following toxin:

Warfarin

A

Vitamin K

plasma (if active bleeding)