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Med Chem > Topical antifungals > Flashcards

Topical antifungals Flashcards

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1
Q

Non-irritating & non-toxic

Present in perspiration & sweat

A

Propionic acid

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2
Q

0.01% fungicidal

A

Propionic acid

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3
Q

Used as fungicide in adhesive tapes

A

Zinc proprionate

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4
Q

Caprylates

A

Sodium caprylate

Zinc caprylate

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5
Q

Desenex

A

Undecylenic acid

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6
Q

Cruex

A

Undecylenic acid

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7
Q

10-undecenoic acid

A

Undecylenic acid

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8
Q

Obtained frm destructive distillation of Castor oil (ricinoleic acid)

A

Undecylenic acid

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9
Q

Tx athlete’s foot

A

Undecylenic acid

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10
Q

Glyceryl triacetate

A

Triacetin

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11
Q

Enzactin

A

Triacetin

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12
Q

Fungacetin

A

Triacetin

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13
Q

Fungicide

Colorless oily liquid that release Acetic acid upon hydrolysis

A

Triacetin

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14
Q

Antifungal

Keratolytic

A

Salicylic acid

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15
Q

m-hydroxyphenol

A

Resorcinol

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16
Q

Antiseptic

Keratolytic

A

Resorcinol

17
Q

Only anti fungal that cannot penetrate skin

A

Benzoic acid

18
Q

Should be used in combination to provide therapeutic effect

A

Benzoic acid

19
Q

Interfere w/ cell membrane integrity & function in susceptible fungi

A

Phenol & deriv

20
Q

Halotex

A

Haloprogin

21
Q

White to pale yellow

Photosensitive 1% cream

A

Haloprogin

22
Q

Tx superficial tinea infxn

A

Haloprogin

23
Q

Vioform

A

Clioquinol

24
Q

Spongy
Light-sensitive
Yellowish white powder

A

Clioquinol

25
Q

Clioquinol is used as substitute for

A

Iodoform

26
Q

Tx jock itch & athlete’s foot

A

Clioquinol

27
Q

3% tx vaginitis

A

Clioquinol

28
Q

Loprox

A

Ciclopirox olamine

29
Q

Topical broad spectrum antifungal

A

Ciclopirox olamine

30
Q

AOC cutaneous candidiasis

A

Ciclopirox olamine

31
Q

AOC Tinea corporis, cruris, pedis, versicolor

A

Ciclopirox olamine

32
Q

2nd line agt for Onychomycosis

A

Ciclopirox olamine

33
Q

Low conc: blocks transport of amino acids into the cell

A

Ciclopirox olamine

34
Q

High conc: lost of mem integrity & cellular constituents

A

Ciclopirox olamine

Med Chem (5 decks)

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