Other antifungals Flashcards
1
Q
Inhibitor of D14 reductase & D7-D8 isomerase
A
Morpholines
2
Q
Morpholine eg
A
Amorolfine
3
Q
Acts as tight binding noncompetitive inhibitor of inositol phosphorylceramide synthase
A
Aureobasidins
4
Q
Essential for fungal sphingolipid biosynthesis
A
IPC synthase
5
Q
Can cause life threatening infx of immunocompromised pts
A
Opportunistic fungal infxn
6
Q
Group of fungal disease w/c both the skin & SC tissues are involved
A
Subcutaneous fungal infxn
7
Q
Soil saprophytes of low grade virulence & invasive ability
A
Subcutaneous fungal infxn
8
Q
Formidable barrier for drug penetration
A
Skin
9
Q
Fatty acids & deriv all have antifungal axns due to
A
Sebum fraction
10
Q
Salt form are fungicidal
A
SAR
11
Q
High mol wt fatty acids have lower volatility
A
SAR
