topic 6 cell division Flashcards
cell cycle s 3 main phases
-interphase
-mitosis
-cytokenisis
interphases 3 phases
-G1 phase - cell grows and makes new proteins to replicate organelles
-S phase - dna is replicates
-G2 phase - cell continues to grow and replixated DNA is checked for
if any chromosomes r damaged during G2
at what stage in interphase does the cell replace its energy store
s phase
2 parts of mitotic phase
mitosis- where chromosomes r seperated into 2 nuclei
cytokenisis- where cell divides into 2
what stage does the cell enter if exits the cycle
G0
ehy does a cell enter G0
- if the cell is fully differntiated
-Dna is damaged out a certain point the cell is no longer able to divide when this happens the cell is called senscent cells - some cells enter g0 temporarily these cells can then be triggered to reenter the cell cycle during an infection
3 checkpoints
G1 checkpoint- checks cell has chemicals needed for replication and damage to DNA and if cell has grown to correct size
G2 checkpoint- checks DNA has been replicated without any errors if the cell does it tries to repair them. checks for dna damage and cell had grown to correct size
Metaphase checkpoint- each chromosome checked to ensure they are assembled correctly on mitotic spindle
what happens if a cell fails a checkpoint
enters G0
what are chromosomes
structures located inside the nucleus of animal and plant cells consisting of DNA tightly coiled around proteins called histones
How many chromosomes do humans have?
- Chromosome divided into 23 pairs.
What are the first 22 pairs of chromosomes called
autosomes (identical in both males and females)
what is the 23rd pair known as?
Sex chromosome
what are the two chromatids in each chromosome held together by?
centromere
How many pairs of chromosomes do diploid cells have?
Two copies of each chromosome one from each parent
What is the total number of chromosomes in a diploid cell described as?
2n
How many copies of each chromosome do haploid cells carry?
One copy of each chromosome
what is the total number of chromosomes in a haploid cell described as?
n
Once cells have completed interphase, what do they undergo
Mitosis and cytokinesis
what takes place during the end phase ( mitotic phase )
Cytokinesis and mitosis
mitosis is used by organisms for many processes, including
Growth
Replacement of damaged or dead tissues
Asexual reproduction
development of body plans
Production of stem cells
can we see chromosomes in interphase?
No, as they are in the nucleus as chromatin so they have a loose open structure
Four stages of mitosis
prophase
Metaphase
Anaphase
Telophase
Prophase (mitosis)
The chromosomes condense
A pair of centrioles migrate to opposite poles of the cell
Each centriole starts forming spindle fibers which attach the centromere of each chromosome
Spindle fibers start to move the chromosomes towards the center of the cell
Nucleus disappears a nuclear envelope starts to break down so chromosomes are free in cytoplasm
Metaphase (mitosis)
chromosomes lineup at equator
Spindle apparatus has completely formed
each chromosome attaches to the spindle by their centromere
At metaphase checkpoint each chromosome is checked to ensure it is attached to spindle