Topic 4 - Natural Selection and Genetic modification Flashcards

1
Q

Natural selection

A

Survival of the fittest ( Characteristics ) leading to evolution

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2
Q

What are some natural selection pressures?

A

Predation, competition for resources and disease

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3
Q

Bacterial evidence for Evolution

A

Antibiotic resistance provides evidence for evolution because it makes the bacteria better adapted to an environment where selection pressures are present.

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4
Q

Fossil evidence for human evolution

A
  • ## Humans and chimpanzees evolved from a common ancestor
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5
Q

Ardi

A

A fossil huminid 4.4Million years old
- structure of feet - climbs trees
- Long arms and short legs ( like an ape)
- Chimpanzee brain
- Walked upright

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6
Q

Lucy

A

Fossil Hominid 3.4 Million years old

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7
Q

Classification

A

organising living organisms into groups

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8
Q

What are the kingdoms in the 5 kingdom classification system?

A

Animals - Fish, mammals, reptiles ect.
Plants - Grasses, trees ect.
Fungi - Mushrooms, toadstools, yeast, mold
Prokaryotes - all single-celled organisms without a nucleus
Protocists ( eukaryotes ) - Eukaryotic single-celled organisms

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9
Q

Prokaryotes vs Eukaryotes

A

Eukaryotic cells contain their DNA in a nucleus and have membrane bound organelles
Prokaryotic cells contain their DNA in the form of circular DNA free in the cytoplasm and also have DNA in plasmids, which are circular.

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10
Q

What are the subsections of the 5 kingdoms?

A

Phylum, class, order, family, genus, species

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11
Q

How have classification systems changed over time?

A

1) T5K is still used but a bit out of date
2) New tech and better understanding of Biochemical processes and genetics.

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12
Q

How has new tech changed our classification systems?

A

We are now able to determine the sequence of DNA bases in different organisms’ genes and compare them. Scientists are also able to compare RNA in a similar way
- This lead to the 3 domain system now in place

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13
Q

How was the 3 domain system created?

A

Proposal made by Carl Woese
Using RNA sequencing, Woese found that some members of the prokaryote kingdom were not as closely related as he thought and that this kingdom should be split into two called Archea and Bacteria - the third domain is Eukarya

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14
Q

What is Archea?

A

Organisms in this domain look similar to bacteria but are actually quite different - as differences in their DNA and RNA sequences show. They were first found in extreme placxes such as hot springs and salt lakes

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15
Q

DOMAIN

What is bacteria?

A

This domain contains true bacteria like E.coli and Staphyloccus

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16
Q

DOMAIN

what is eukarya?

A

This domain includes a broad range of organisms including fungi, plants, animals and protists

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17
Q

How do individiuals in a population show genetic variation?

A

Differences in their alleles - which arive from genetic variation

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18
Q

What are selection pressures and what do they affect?

A

Predation, competition for resources (e.g. food, water, mates) and disease
-> Affect an organism’s chance of surviving and reproducing

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19
Q

How do characteristics that are beneficial against selection pressures become more common in a population over time?

A

1) Individuals with beneficial characteristics against their environment have better chances of survival - so are more likely to breed succesfully
-> Opposite happens with bad characteristics
2) The alleles responsible for beneficial characteristics are more likely to be passed onto the next gen
3)

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20
Q

What is an example of bacteria having random mutations in their DNA?

And natural selection

A

A bacterium becoming more resistant to a particular antibiotic
-> this would cause it to repoduce more times in a host-cell than a non-resistant bacterium
This would cause the allele for antiobiotic resistance to be passed along to offspring - Natural selection - the resistance becomes more common over time

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21
Q

What is an antibiotic

A

A drug designed to kill bacteria or prevent them from reproducing

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22
Q

How does Antibiotic resistance provide evidance for evolution?

A

It makes the Bacteria better adapted to an environment in which antibiotics ( a selection pressure) are present. As a result, antibiotic resistance becomes more common in a population over time.

This is applicable to other species e.g. rats resistant to rat poison

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23
Q

What is a fossil?

A

Any trace of an animal or a plant that lived a long time ago
-> Often found in rocks
-> Deeper rock = older fossil

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24
Q

What theory did charles darwin come up with?

A

The Theory of evolution by natural selection

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25
How did Charles Darwin come up with the theory of evolution by natural selection?
5 Year voyage on HMS Beagle studying plants and animals -> Noticed there was variation in memers of the same species and that those with beneficial characteristics were more likely to survive -> Noticed these could be passed down onto offspring
26
Who is alfred russel wallace?
A scientist working at the same time as Darwin, who also came up with the idea of natural selection
27
What did Russel and Wallace do together?
Published their papers on evolution together -> Although they didnt always agree on the mechanisms on natural selection
28
What are some examples of Wallace's observations and what did they do?
Helped to support the theory of evolution by natural selection -> E.g. He realised that warning colors are used by some species to stop predators eating them (butterflies)
29
What publication gave most attention to the theory of Evolution by natural selection?
"On the Origin of Species" - Darwin, Published in 1859 | Partly why Darwin was better remembered than wallace
30
What aspects of modern biology has the theory of evolution by natural selection?
Classification Antibiotic resistance Conservation
31
How has the theory of evolution of natural selection affected modern classification?
If all living organisms have descended from a common ancestor, then we're all related in some way. -> we now classify organisms based on how closely related they are
32
How has the theory of evolution of natural selection affected antibiotics?
We understand the importance of finishing the course of drugs to prevent resistant bacteria spreading and we know we need to constantly develop new antibiotics to fight newly evolved resistant bacteria
33
How has the theory of evolution of natural selection affected conservation?
Understand the importance of Genetic diversity and how it helps populations adapt to changing environments -> Lead to conservation projects
34
What are hominids?
Human beings and their ancestors they evolved from 6 million years ago
35
What does evidence from fossils suggest about humans and chimpanzees?
That they both evolved from a common ancestor 6 million years ago
36
Who is Ardi and where was she found?
**Ardi is a fossil of the species Ardipithecus ramidus** -> Found in Ethiopia -> 4.4 Million years old
37
What are Ardi's features and what do they suggest?
1) Structure of **feet** suggests she climed trees -> Ape like big toe to grasp branches 2) Long arms and short legs - more ape than human 3) Brain size - similar to Chimpanzees 4) Structure of** legs suggests she walked upright** 5) Hand bone structure suggests she didnt use her hands to walk
38
Who is Lucy and where was she found?
**Lucy is a fossil of the species Australopithecus aferensis** -> Found in Ethiopia -> 3.2 Million years old -> Mixture of human and ape features, more human-like than Ardi
39
What are Lucy's features and what do they suggest?
1) Arched feet - more adapted to walking than climbing - no ape-like big toe 2) Size of arms and legs was between an apes and a humans 3) Brain slightly larger than Ardi's but still Chimp like 4) Structure of Bones and feet suggest she walked upright, but more efficiently than Ardi
40
Who and when organised an expedition to Kenya to look for hominid fossils?
1984 Scientist Richard Leaky -> They discovered many important fossils of Australopithecus and homo species
41
What was one of the finds of Richard Leaky
Turkana Boy
42
Turkana boy
1.6 Million years old skeleton of the species homo erectus -> Mixture of human and ape features, more human than Lucy
43
What were Turkana boy's features and what do they suggest?
1) Short arms and long legs - more human than ape 2) Larger brain size - more human 3) Structure of feet and legs suggested he walked upright - more effeciently than Lucy
44
What are the disadvantages of selective breeding?
1) reduces gene pool - number of different alleles in a population 2) Inbreeding can cause health problems as there is a higher chance of organisms inheriting harmful genetic defects when the gene pool is limited 3) Lower resistance to diseases - group vunerability -> less chance of resistant alleles being present
45
What is tissue culture?
growing cells on an artificial growth medium -> Whole plants can be grown
46
What are the benefits of growing plants via tissue culture?
- Made quickly and in all seasons - Plants produced are genetically identical organisms (clones) - can produce plants witht th same beneficial features
47
# Plant What are the steps for tissue culture?
1) Pick the plant you want to clone (based of characteristics) 2) Remove several small peices of tissue from the parent plant - best results from fast-growing root or shoot tips 3) Grow the tissue in a growth medium containing nutrients and growth hormones -> Done under aseptic conditions to prevent growth of microbes that could harm the plants 4) As the tissues produce roots and shoots they can be transferred to potting compost to carry on growing
48
What is animal tissue culture often used for?
Medical Research - can carry out all sorts opf experiemnts on tissues in isolation
49
Why is animal tissue culture beneficial for medical research?
You can look at the effects of a particular substance or environmental change on the cells of a single tissue, without complications from other processes in the whole organism
50
What are the steps for animal culture
1) Take the sample of tissue you want to study (extracted from the animal) 2) The cells in the sample are seperated from eachother using enzymes 3) They are placed in a culture vessel and bathed in a growth medium containing all the nutrients that they need - allows them to grow and multiply 4) After several rounds of cell division, the cells can be split up again and placed into seperate vessels to encourage further growth | These are then stored for future use
51
What is genetic engineering?
Modifying an organisms' genome (DNA) to produce desireable characteristics -> involves the use of enzymes and vectors (carriers) | Enzymes can be used to cut up or join DNA
52
# Genetic engineering What do restriction enzymes do?
Recognise specific sequences of DNA and cut the DNA at these points - the peices of DNA are left with sticky ends where they have been cut
53
# Genetic engineering What are ligase enzymes used for?
used to join 2 pieces of DNA together at their sticky ends
54
# Genetic engineering what is recombinant DNA?
2 peices of DNA stuck together
55
# Genetic engineering What is a vector and what are the 2 types of vector?
**A vector is something that is used to transfer DNA into a cell** - Plasmids and Viruses
56
# Genetic Engineering What are plasmids?
Small, Circular molecules of DNA that can be transferred between bacteria
57
# Genetic Engineering How do viruses transfer DNA?
They insert DNA into the organisms they infect
58
What are the steps for genetic engineering?
1) The **DNA you want to insert** (e.g. the gene for human insulin) and the **vector DNA** is **cut out/(vector opened)with a restriction enzyme** 2) The Vector DNA and DNA you're inserting are left with sticky ends and then mixed together with ligase enzymes 3) The Ligases join the peices of DNA together to make **recombinant DNA** 4) The recombinant DNA (i.e. the vector containing new DNA) is inserted into other cells, e.g. bacteria 5) These cells now can use the gene you inserted to make the protien you want
59
What is an example of genetic engineering?
Bacteria containing the gene for human insulin can be grown in huge numbers in a fermenter to produce insulin for people with diabetes
60
How can genetic engineering be used in agriculture?
Crops can be genetically modified to be resistant to herbicides ( chemicals that kill plants). - Means farmers can spray their crops to kill weeds, without harming the crop itself - increasing yield
61
What are some uses of genetic engineering in medicine? | Apart from insulin
Researchers have managed to transfer human genes that produce useful proteins into sheep and cows. *E.g. human antibodies used in therapy for illnesss like arthiritis, some types of cancer, and multiple sclerosis* These protiens can then be extracted from the animal e.g. from their milk | Animals that have organs suitible for human transplant - made in future
62
What are the concerns about the genetic engineering of animals?
1) hard to predict what effect modifying its genome will have on the organism - many genetically modified embryos don't survive and some genetically modified animals suffer from health problems later in life
63
What are the concerns about genetically modifying crops?
1) Transplanted genes may get out into environment - e.g. a herbicide resistance may be picked up by weeds, creating a new "superweed" variety 2) Could adversely affect food chains - or even human health
64
what are GMOs and what are they used for?
**Genetically modified organisms** - Used to help provide food for many people in the world that suffer from hunger
65
# GMOs Why might people want to genetically engineer crops?
To make them resistant to insect pests - improve crop yields and reduce need for chemical pesticides -> E.g. a bacterium called Bacillus thuringiensis (Bt) which produces a toxin which kills many of the insect larvae that are harmful to crops | or could help resistance to droughts
66
How does Bt work?
The gene for the Bt toxin is inserted into crops, such as corn and cotton, which then produce the toxin in their leaves and stems - making them less resistant to insect pests ( the toxin is specific to insects so will not harm other organisms)
67
What are the downsides of Bt
The insects that feed on the crops are constantly exposed to the toxin, so there's a danger they will develop a resistance and no longer be killed by it. - farmers use a variety of insecticides to try and stop this from occuring | Also the long term effects of exposure to Bt are unknown
68
Why must global food production increase?
The population is rising rapidly - we all need access to enough food that is safe for us to eat and has the right balance of nutrition - Called "food security"
69
What is an example of crops being genetically engineered to help combat certain deficiency diseases?
Golden rice has been genetically engineered to produce a chemical thats converted in the body into vitamin A
70
What are the agruments against GMOs being used to combat world hunger?
1) Many argue that people go hungry because they cannot afford food, not because there isnt enough, so they think they should combat poverty first 2) There are fears that countries will be reliant on others that sell GM seeds 3) Sometimes poor soil is the reason why crops fail, and even GM crops wont survive
71
What other techniques (apart from GMOs) can be used to help increase food production
Fertilisers or Biological control
72
How can fertilisers be used to help increase food production
Fertilisers contain minerals essential for plant growth - replenish poor soil (replace ions lost to previous crops)
73
What is the main problem with fertilisers?
Eutrophication in rivers and lakes
74
What is biological control?
Using other organisms (i.e. predators and paracites) to reduce pest numbers
75
What is an example of biological control?
Cane toads were introduced in Australia to eat beatles that were damaging crops
76
What are the benefits of biological control?
Longer-lasting effects than chemical pesticides and can be less harmful to wildlife
77
What are the disadvantages of biological control?
Introducing new organisms can cause problems - e.g. Cane toads are now a pest themselves in Australia as they poison the native species that eat them
78
When an ancient stone tool or hominid fossil is found, how can scientists work out how old it is?
1) Structural features - Simpler = older 2) Using stratigraphy 3) Stone tools are often found with carbon-containging material e.g. a wooden handle - carbon-14 dating can be used to date this material
79
What is stratigraphy?
The study of rock layers - Older rocks are normally found below younger layers = tools or fossils in deeper layers are usually younger
80
What is a pentactyl limb?
A limb with 5 digits