TOPIC 3: Membranes Flashcards
What are the 4 factors that affect membrane fluidity?
1) tempurature
too cold=more viscous,
too hot=more fluid-like
2) fatty acid tail saturation
Saturated=more viscous
Unsat.=more fluid
3) tail length
Longer tail=more viscous
Shorter=more fluid
4) prescense of steroids (helps to stabilize fluidity)
Why do animal cells have cholesterol in their membrane bilayer?
The cholesterol in the bilayer moderates tempurature and ensures that the phopholipids aren’t too close or far from eachother.
What does the cholesterol in the bilayer help revent
Prevents:
1) freezing (stops phospholipids from being too close together)
2) melting (by restraining phospholipid movement and filling in the gaps)
Cell membranes have a variation in lipid composition due to what?
Adaptations to environmental conditions
Can organism change their lipid composition as tempurature changes?
Yes
What are two types of membrane proteins?
- peripheral proteins
- integral proteins
What are peripheral proteins?
Proteins in which that hang out on top or on the surface of the membrane (they touch the membrane)
They are polar amino acids
What are integral proteins
Proteins that are penetrate the hydrophobic core. These proteins are INTEGRATED and embedded in the membrane
These proteins include hydrophillic (1 or 2 parts) and hydrophobic parts
If the integral protein spans the whole membrane then its called ______
Transmembrane protein
Describe the structure of a transmembrane protein
It consists of a sequence of amino acids (it includes polar and non polar chunks and it goes in a pattern)
Hydrophilic region and hydrophobic regoin to match the region outside (refer to the diagram in the notes)
What are the 6 functions of membrane proteins?
- help molecules transport across membrane
- enzymes
- signalling
- cell to cell recognition (recognizes molecules)
- cell-cell joining)
- anchoring
What matters in the selectively permeable bilayer?
- size
- polarity
- charge
What kind of molecules can pass through the lipid bilayer?
- small non polar molecules (O2, N2, CO2)
(They get in very fast) - small uncharged polar molecules (H2O, glycerol) (slower acces )
What kind of molecules have a hard time or can’t pass through the membrane?
- ions (will be fully rejected) Cl-, K+, Na+
- large uncharged polar molecules
(Glucose sucrose)
What are the two types of transport in a cell?
Passive and active transport
What is passive transport?
Transport that is based on diffusion and moves with/down the concentration gradient (high [ ] to low [ ])
Imagine a ball rolling down an incline. The high represents the concentration (high and low)
What is active transport?
Transport in which that requires energy to go from a place of low [ ] to a place of high [ ]
- moves agaisnt or up the concentration gradient
Imagine pushing a ball up an incline, it requires energy to push the ball to get to a high [ ]