Topic 3 - Innate Immune Sensing of Danger

Question 1

Phagocyte

Answer 1

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Question 2

C

Answer 2

• Most complement proteins are named with a “C” and a number.
  
  • Ex) C1, C2, C3…

Question 3

Opsonin

Answer 3

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Question 4

Anaphylatoxin

Answer 4

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Question 5

Chemoattractant

Answer 5

-

Question 6

Complement fixation

Answer 6

(Binding of C3b to pathogen surface)
- Is when the pathways converge, and is the MOST
IMPORTANT FUNCTION of complement activation.

Question 7

CR#

Answer 7

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Question 8

Explain what is meant by the following statement: “Complement works in a cascade fashion that amplifies as it proceeds.”

Answer 8

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Question 9

List the major advantage that complement has compared to antibody in tagging pathogens for disposal.

Answer 9

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Question 10

List and define the 4 main functions that the complement proteins can perform for the immune system.

Answer 10

1) . Opsonize
2) . Chemoattractant
3) . Form a pore by lyses
4) . Be Anaphylatoxins