Topic 2 - Disorders of Transmission and Person Centred Practice

Question 1

How will muscles be affected by disturbances at the myoneural junction?

Answer 1

May result in weakness.
Uncoordinated movement.
Fatigue.

Question 2

Myasthenia Gravis - Symptoms

Answer 2

Muscles weakness.
Eye muscles often involved first.
Next facial and mastication muscles.
Complications when respiratory muscles affected.

Question 3

Myasthenia Gravis - Pathophysiology

Answer 3

Autoimmune

Destruction of ACh receptors

Question 4

MS - Pathophysiology

Answer 4

Demyelinating
Chronic inflammation of CNS
Disruption of transmission - partial/full

Question 5

MS characteristics

Answer 5

Most frequent neuro disease in young/middle aged adults.
Huge variation of symptoms.
Near normal life expectancy.

Question 6

MS - Classification

Answer 6

Benign - single event ,no progression in 10 years.
Relapsing remitting - most common.
Secondary progressive - R/R then steady worsening without relapse.
Primary progressive - steady worsening without relapse

Question 7

Guillain Barre Syndrome - Characteristics

Answer 7

Autoimmune of PNS.
Gradual recovery after a few weeks.
40-60% case occur after bacterial infection.

Question 8

Guillain Barre Syndrome - Clinical features

Answer 8

Weakness.
Respiratory muscle weakness.
Typically begins with peripheral paraesthsia (glove/stocking).
Cranial nerve involvement 50% cases.

Question 9

Guillain Barre Syndrome - Secondary impairments/complications

Answer 9

Disuse/atrophy. 
CV deconditioning. 
Stiffness. 
DVT. 
Infection/pneumonia. 
Mental and social issues

Question 10

Guillain Barre Syndrome - Recovoery

Answer 10

Hugely variable.

Median time for complete recovery 6 months

Question 11

Guillain Barre Syndrome - - Treatment

Answer 11

IV immunoglobulin.

Physio

Question 12

Person Centred Practice

Answer 12

Work with patient to set SMART goals.
Active listening, explanation.
Treat the person, not the problem.
Comes back to ICF.