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FINALS PHARMA > TOPIC 11 > Flashcards

TOPIC 11 Flashcards

1
Q

Growth hormone
Thyroid stimulating hormone
Adrenocorticotropic hormone
Gonadotropin follicle stimulating Hormone
Luteinizing hormone
Prolactin

A

Anterior Pituitary gland

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2
Q

Antidiuretic hormone
Oxytocin

A

Posterior pituitary gland

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3
Q

Thyroid releasing hormone (TRH)
Corticotropin releasing hormone (CRH)
Growth hormone-releasing hormone (GH_RH)
Growth hormone -inhibiting hormone (GH-IH)

A

Hypothalamus

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4
Q

Thyroxine (T4)
Triiodothyronine ( T3)

A

THYROID GLAND HORMONES

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5
Q

Controls metabolic rate and activity of nearly every tissue and organ
Increase CO
Increase 02 consumption
Carbohydrate use , proteins and fats
Affect heat regulation and menstrual cycle

A

Thyroid hormone

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6
Q

HYPOTHYROIDISM cause in adult_______children_______

A

Myxedema ( adult)
Cretinism ( children)

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7
Q

Lethargy
Puffy eyelids and face
Thick tongue
Slow speech with hoarseness
Lack of perspiration
Slow pulse
Cold intolerance
Abnormal menses

A

HYPOTHYROIDISM SX

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8
Q

Drug of choice for replacement therapy
Increases T3 and T4
Given per orem

A

Levothyroxine sodium (Levothyroid, Synthroid)

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9
Q

Tachycardia
Chest pain
Palpitations
Excess sweating

A

HYPERTHYROIDISM SX

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10
Q

Reduce excess T3 and T4
Thiourea derivatives
1. Propylthiouracil (PTU)
2. Methimazole(Tapazole)

A

HYPERTHYROIDISM DRUG THERAPY

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11
Q

Inhibits thyroid hormone synthesis
PO

A

METHIMAZOLE (TAPAZOLE)

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12
Q

Inhibits conversion of T4 and T3
Maybe used before surgery or radioactive iodine tx palliative control
Toxic goiter
PO

A

PROPYLTHIOURACIL (PTU)

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13
Q

Reduce size and vascularity of thyroid gland

A

STRONG IODINE SOLUTION (LUGOL’S SOLUTION)

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14
Q

Regulates calcium in the blood

A

Parathyroid hormone

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15
Q

Mobilizing calcium from bones
Promotes Ca absorption from the intestine
Promotes Ca reabsorption from the renal tubule

A

Parathyroid hormone

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16
Q

PTH deficiency
Vitamin D deficiency
Renal impairment
Diuretic therapy

A

Hypocalcemia

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17
Q

Promote calcium replacement in the Gl tract
Promote reabsorption of calcium from the renal tubules
Activates Vitamin D

A

PTH replacement

18
Q

Vitamin D analogue that promotes calcium absorption from the Gl tract and secretion of Calcium from bones to the bloodstream

A

Calcitriol-PO

19
Q

Treatment of Paget disease
HyperPARAthyroidism
Hypercalcemia Subcutaneous

A

CALCITONIN - human (CIBACALCIN)
CALCITONIN - salmon (MIACALCIN)

20
Q

Treatment of Paget disease
HyperPARAthyroidism
Hypercalcemia
PO

A

CINACALCET ( SENSIPAR)

21
Q
  1. LISPRO (Humalog)
  2. ASPART (Novolog)
  3. GLULISINE (Apidra)
A

RAPID ACTING INSULIN

22
Q
  1. INSULIN REGULAR (Humulin R)
A

SHORT ACTING INSULIN

23
Q
  1. ISOPHANE, NPH (Humulin N, Novolin N)
  2. SUSP LENTE (Humulin L, Novolin L)
A

INTERMEDIATE ACTING INSULIN

24
Q
  1. ULTRALENTE INSULIN
  2. INSULINE GLARGINE (Lantus
A

LONG ACTING INSULIN

25
Q
  1. HUMULIN 70/30
  2. INSULIN ISOPHANE NPH 50/50
  3. HUMALOG 75/25
A

INSULIN COMBINATIONS

26
Q
  • Decrease hepatic production of glucose from stored glycogen
  • Increases insulin receptor sensitivity
  • Decrease absorption of glucose in the small intestine
A

METFORMIN (Glucophage)

27
Q

Improves glucose control and decrease insulin resistance

A

ALPHA GLUCOSIDASE INHIBITOR

28
Q

Insulin enhancing agents
Improves blood glucose control and increase insulin sensitivity

A

THIAZOLIDINEDIONES

29
Q

Produced corticosteroids:
Glucocorticoids ( Cortisol)
Mineralocorticoids (Aldosterone)

A

Adrenal cortex

30
Q

Promote sodium retention and potassium excretion

A

Corticosteroids

31
Q

Results from adrenal insufficiency

A

Addison’s disease

32
Q

Results from hypersecretion of the adrenal glands

A

Cushing’s syndrome

33
Q

Cause sodium retention
Water retention
Potassium loss
Increase blood pressure

A

Glucocorticoids

34
Q

Has antiinflammatory, anti-allergy, antistress effect

A

Cortisol /Cortisone drugs

35
Q

Multiple sclerosis
Rheumatoid arthritis
Myasthenia gravis

A

Indications for Glucocorticoid therapy

36
Q

Adrenal insufficiency
PO

37
Q

Adrenal insufficiency
Inflammation
PO, IV, Rectal

A

HYDROCORTISONE

38
Q

Anti-inflammatory
Immunosuppressive effect
PO, IM, IV

A

PREDNISOLONE

39
Q

Anti-inflammatory
Anti-asthma
PO, IM, IV

A

BETAMETHASONE

40
Q

Controlled by renin-angiotensin system
Promotes fluid balance by promoting renal reabsorption of sodium from renal tubules

A

Mineralocorticoids

41
Q

Treatment for Cushing syndrome

A

Glucocorticoid Inhibitor

42
Q

inhibit synthesis of glucocorticoid
PO

A

KETOCONAZOLE

FINALS PHARMA (5 decks)

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