Topic 1 - Basic Chemistry Review, Cells & Tissues Flashcards

1
Q

Ultramicroscopic building blocks of matter. Contain a nucleus (protons and neutrons) and surrounding electrons. The number of protons and electrons are equal.

A

Atoms

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2
Q

When two or more atoms bond to form a stable structure.

A

Molecule

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3
Q

A substance made of different atoms (e.g. H2O, CH4).

A

Compound

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4
Q

A substance made entirely of the same atoms (e.g. oxygen).

A

Element

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5
Q

An atom with an unequal number of protons and electrons (it therefore has a positive and negative charge).

A

Ion

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6
Q

An atom or molecule with an unpaired electron.

A

Free Radical

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7
Q

There is energy stored in the bonds between atoms and molecules. A ________ ________ occurs when these bonds are formed or are broken.

A

Chemical Reaction

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8
Q

The sum of all chemical reactions occurring in the body.

A

Metabolism

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9
Q

The building phase of metabolism. Simple molecules are combined to make more complex ones. This requires/uses energy.

A

Anabolism

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10
Q

The breaking down phase of metabolism. Complex molecules are broken down into simpler ones. This produces/releases energy.

A

Catabolism

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11
Q

The “energy currency” of the body that provides a form of energy that is usable by all cells.

A

ATP (aka. Adenosine Triphosphate)

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12
Q

The energy stored in ATP is “_____” to perform many very important body functions including:
- Muscle contraction
- Cell division
- Movement of substances across cell membranes
- Making larger molecules out of smaller molecules

A

“Spent”

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13
Q

The energy needed to reform ATP is “______” by breaking down (catabolizing) food.

A

“Gained”

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14
Q

The process of getting the energy needed to perform various functions by breaking ATP which releases energy.

A

Consuming / “Spending” ATP

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15
Q

The process of attaching the phosphate back onto ADP to reform ATP which requires energy.

A

Reforming / “Gaining” ATP

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16
Q

What 3 substances do cells get energy from?

A

1) Carbohydrates
2) Fats
3) Proteins

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17
Q

Substances used to make energy or reform ATP.

A

Energy Substrates

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18
Q

Depending on the cell, the demand for energy and the energy substrates available, different substrates will be used.

A

Cellular Preference

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19
Q

A series of reactions that transfer energy from food to ATP.

A

Cellular Respiration

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20
Q

Cellular respiration that happens without oxygen present/used.

A

Anaerobic

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21
Q

Cellular respiration that happens with oxygen present/being used.

A

Aerobic

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22
Q

With ____________ metabolism, cells use glycogen or blood glucose and the energy released in breaking it down is used to reform ADP + Pi into ATP. This is the preferred energy substrate.

A

Carbohydrate Metabolism

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23
Q

The process of making ATP from glucose, occurring in the cell cytoplasm. A molecule of glucose is broken into 2 molecules of pyruvic acid and 2 ATP.

A

Glycolysis

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24
Q

Glycolysis in which pyruvic acid enters the mitochondria and a series of reactions yield 26-28 more ATP. This occurs in the ________ of oxygen.

A

Presence

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25
Q

Glycolysis in which pyruvic acid does not go into the mitochondria. It is converted into lactic acid, which quickly converts to lactate. This occurs in the _______ of oxygen.

A

Absence

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26
Q

The process of fat being used to generate ATP, but only in the presence of oxygen.

A

Fat Metabolism

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27
Q

The breakdown of stored fat into glycerol and fatty acids, which can be used to make ATP. The amount of ATP generated depends on the size of the fat.

A

Lipolysis

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28
Q

Liver cells make ______ ______, which are used by other cells (e.g. heart, nervous system, kidneys) to make ATP.

A

Ketone Bodies

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29
Q

The process of proteins being broken down into amino acids. This takes longer and produces extra wastes. Only small amounts are used to generate ATP.

A

Protein Metabolism

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30
Q

Substances needed for body structure and function.

A

Nutrients

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31
Q

A key element that cells need in order to function.

A

Oxygen

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32
Q

Compounds that contain no carbon, such as water, acids, bases and many salts.

A

Inorganic Compounds

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33
Q

Accounts for about 65% of body weight and nearly all chemical reactions occur in this.

A

Water

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34
Q

A mixture of two or more substances.

A

Solution

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35
Q

The part of a solution that dissolves the substance of lesser amount (usually the greater amount).

A

Solvent

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36
Q

The part of a solution that is being dissolved (usually the lesser amount).

A

Solute

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37
Q

When inorganic compounds dissolve in water, they __________ into ions and become surrounded by water molecules.

A

Dissociate

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38
Q

A substance that dissociates into one or more hydrogen ions (H+).

A

Acid

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39
Q

A substance that dissociates into one or more hydroxide ions (OH-).

A

Base

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40
Q

A substance dissociates into positive or negative ions (no H+ or OH-).

A

Salt

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41
Q

The more hydrogen ions (H+) dissolved in a solution, the more ______ it is.

A

Acidic

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42
Q

The more hydroxide ions (OH-) dissolved in a solution, the more _____ it is.

A

Basic (aka. Alkaline)

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43
Q

The scale in which acids and bases are ranked depending on how strong or weak they are. Values range from 0-14, with 7 being neutral. The body doesn’t tolerate significant changes in this.

A

pH Scale

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44
Q

Compounds containing carbon, such as ATP, lipids, carbohydrates and nucleic acids.

A

Organic

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45
Q

Large, complex molecule structures made up of amino acids.

A

Proteins

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46
Q

Match the different types of proteins with their role.
1) Contractile
2) Transport
3) Structural
4) Immunological
5) Catalytic
6) Regulatory

A) Framework of body parts
B) Hormones
C) Shorten muscle cells
D) Regulate chemical reactions
E) Carry substances in the body
F) Help fight invading pathogens

A

1) Contractile = C) Shorten muscle cells
2) Transport = E) Carry substances in the body
3) Structural = A) Framework of body parts
4) Immunological = F) Help fight invading pathogens
5) Catalytic = D) Regulate chemical reactions
6) Regulatory = B) Hormones

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47
Q

Fats and other fat-like substances that are necessary for many different body functions.

A

Lipids

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48
Q

Energy substrates of lipids.

A

Fatty Acids

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49
Q

The storage form of excess calories in lipids.

A

Triglycerides

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50
Q

Function primarily as an energy substrate and include sugars and starches.

A

Carbohydrates

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51
Q

What is the storage form of glucose?

A

Glycogen

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52
Q

What are 2 types of nucleic acids?

A

1) DNA
2) RNA

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53
Q

Your genetic material that controls most cell activities and is stored in the nucleus.

A

DNA

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54
Q

Relays genetic instructions to guide protein synthesis.

A

RNA

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55
Q

The smallest functional unit that can retain the necessary characteristics for life.

A

Cell

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56
Q

A group of similar cells that perform a similar function.

A

Tissue

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57
Q

What are the 4 major groups of tissue?

A

1) Epithelial
2) Connective
3) Muscular
4) Nervous

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58
Q

Tissue that covers body surfaces, lines hollow organs and forms glands (e.g. skin, inner surface of stomach).

A

Epithelial

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59
Q

Tissue that gives structure and connects things (e.g. fascia).

A

Connective

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60
Q

Specialized tissue that uses ATP to produce force or contract.

A

Muscular

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61
Q

Tissue that helps make up the nervous system.

A

Nervous

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62
Q

A part of the body composed of at least two different kinds of tissue. All the tissues involved that contribute to a specific function or activity.

A

Organ

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63
Q

A group of organs related to each other that perform functions together.

A

Organ System

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64
Q

Organ systems operating together.

A

Organism

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65
Q

The condition of balance in the body’s internal environment due to the constant interaction of the body’s many internal regulatory processes. The different parts of the body operate within specific parameters and mechanisms keep the internal environment within those limits.

A

Homeostasis

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66
Q

The body is _______ and all structures contribute to maintaining homeostasis. When something disrupts homeostasis, there are mechanisms that will have the ________ effect. Most disruptions are mild and _________ and the return to homeostasis is relatively quick.

A

Dynamic
Opposite
Temporary

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67
Q

A cycle of events in which the internal environment is monitored, evaluated, changed, re-monitored, re-evaluated, etc.

A

Feedback Systems (aka. Loops)

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68
Q

The variable being monitored (e.g. body temperature).

A

Controlled Condition

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69
Q

Whatever disrupts or changes the controlled condition. These disruptions can be internal or external.

A

Stimulus

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70
Q

What are the 4 components of a feedback system?

A

1) Sensor/Receptor
2) Transmission Pathways
3) Control Centre
4) Effector(s)

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71
Q

A structure that monitors changes in a controlled condition. They detect chemical, electrical and mechanical changes. It sends information to the control centre via a transmission pathway.

A

Sensor/Receptor

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72
Q

The nervous and blood vessel pathways that relay messages between the components of a feedback system.

A

Transmission Pathways

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73
Q

Comprises the nervous and endocrine systems and sets the range of values within which the controlled condition should be maintained. Evaluates the input received, determines the body’s response, and sends commands.

A

Control Centre

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74
Q

The structure that produces a response to a given stimulus based on the commands it receives.

A

Effector

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75
Q

The inside of the body is not _______, therefore homeostatic mechanisms also function to maintain key differences in the body.

A

Uniform

76
Q

Reverse changes in the internal environment. They are very stable and the most predominant system.

A

Negative Feedback System

77
Q

Strengthen changes in the internal environment. They are inherently unstable and the most uncommon system. Must have a mechanism that shuts down the response.

A

Positive Feedback System

78
Q

The adjustment of an organism to its environment for a good reason.

A

Adaptation

79
Q

The adjustment of an organism to counterbalance a defect.

A

Compensation

80
Q

A flexible, sturdy barrier surrounding the cell contents that separates the cell from the external environment. Contains membrane proteins and is involved in communication between cells and their environment.

A

Plasma (aka. Cell) Membrane

81
Q

Allowing some substances to pass through (in and out) and not others.

A

Selectively Permeable

82
Q

Fluid inside the cell.

A

Intracellular Fluid (aka. Cytosol)

83
Q

Fluid inside the cell.

A

Intracellular Fluid (aka. Cytosol)

84
Q

Fluid outside the cell containing many substances that the cell extracts based on its needs.

A

Extracellular Fluid

85
Q

Fluid outside the cell containing many substances that the cell extracts based on its needs.

A

Extracellular Fluid

86
Q

What are the 3 types of extracellular fluid?

A

1) Interstitial Fluid
2) Plasma
3) Cerebrospinal Fluid

87
Q

Extracellular fluid that exists between cells.

A

Interstitial Fluid

88
Q

Extracellular fluid in blood vessels.

A

Plasma

89
Q

Extracellular fluid surrounding the brain and spinal cord.

A

Cerebrospinal Fluid

90
Q

Proteins embedded within the membrane or attached to one side of the membrane (inside or outside).

A

Membrane Proteins

91
Q

________ proteins function as:
- Selective channels
- Receptors
- Identify the cell
- Strengthen & support cell membranes

A

Membrane

92
Q

Finger-like projections of the plasma membrane that increase surface area and absorption of nutrients.

A

Microvilli

93
Q

The contents of a cell (everything inside the plasma membrane, not including the nucleus). Functions as storage and cell metabolism.

A

Cytoplasm

94
Q

What are the 2 components of the cytoplasm?

A

1) Intracellular Fluid/Cytosol
2) Organelles

95
Q

A network of protein filaments within the cytosol.

A

Cytoskeleton

96
Q

Some functions of the ____________ include:
- Structural framework for cell shape
- Scaffold for the organization & movement of organelles
- Force transmission
- Cell movement

A

Cytoskeleton

97
Q

A rounded structure usually located near the centre of the cell that is responsible for the cell’s metabolism, growth and reproduction. Contains the cell’s DNA.

A

Nucleus

98
Q

Nuclei are present in all human cells except for ___ _____cells.

A

Red Blood

99
Q

The site of protein synthesis.

A

Ribosomes

100
Q

The site of protein synthesis where ribosomes are attached.

A

Rough Endoplasmic Reticulum (rER)

101
Q

Makes lipid molecules, regulates calcium within the cell and regulates metabolism.

A

Smooth Endoplasmic Reticulum (sER)

102
Q

Processes, sorts, packages and delivers molecules to the plasma membrane or around the cell.

A

Golgi Complex (aka. Apparatus, Body)

103
Q

Break down substances that the cell has taken in or normal parts of the cell that are damaged.

A

Lysosomes

104
Q

Power plants of the cell that transform organic compounds into ATP that is easily accessible to the cell.

A

Mitochondria

105
Q

Short, hair-like projections extending from the surface of the cell. Their movement causes steady movement of fluid/particles along the cell surface.

A

Cilia

106
Q

Similar to cilia, but longer and they move the cell.

A

Flagella

107
Q

What are the 2 types of membrane transport?

A

1) Passive Transport
2) Active Transport

108
Q

A type of membrane transport in which no energy is needed to move the substance across a membrane down its concentration gradient.

A

Passive Transport

109
Q

A type of membrane transport in which energy is needed to move the substance across a membrane against its concentration gradient.

A

Active Transport

110
Q

A difference in the concentration of a chemical from one place to another. It is formed and maintained by moving substances in and out, as well as being selectively permeable.

A

Concentration Gradient

111
Q

What are the 2 types of passive transport?

A

1) Diffusion
2) Osmosis

112
Q

Movement of molecules across the plasma membrane down their concentration gradient from an area of high concentration to an area of low concentration.

A

Diffusion

113
Q

A type of diffusion in which molecules move straight through the plasma membrane.

A

Simple Diffusion

114
Q

A type of diffusion in which molecules go through membrane proteins across the plasma membrane.

A

Facilitated Diffusion

115
Q

Movement of water across a selectively permeable plasma membrane from an area of high water concentration to an area of low water concentration.

A

Osmosis

116
Q

T/F - Osmosis only occurs when a membrane is permeable to water and not to certain solutes.

A

True

117
Q

What are the 3 types of active transport?

A

1) Endocytosis
2) Phagocytosis
3) Exocytosis

118
Q

A fast way of moving substances.

A

Transport in Vesicles

119
Q

A small spherical sac.

A

Vesicle

120
Q

A type of active transport in which extracellular materials are brought into a cell in a vesicle formed by the plasma membrane.

A

Endocytosis

121
Q

A type of active transport in which vesicles formed in a cell fuse with the plasma membrane and release materials out of the cell.

A

Exocytosis

122
Q

A type of active transport and a form of endocytosis in which the cell engulfs large solid particles like bacteria, viruses and worn-out cells.

A

Phagocytosis

123
Q

What are the 3 types of cell junctions?

A

1) Tight Junctions
2) Anchoring Junctions
3) Gap Junctions

124
Q

A type of junction that prevents the passage of substances between cells.

A

Tight Junctions

125
Q

A type of junction that anchors cells to one another.

A

Anchoring Junctions

126
Q

A type of junction that provides channels to allow substances to pass between cells, enabling rapid communication.

A

Gap Junctions

127
Q

A type of tissue that functions as a selective barrier, secretory and protective surface. It has a free/apical, lateral and basal surface. It has no blood supply, but does have a nerve supply.

A

Epithelial Tissue

128
Q

A thin layer that anchors the epithelial cells to the underlying connective tissue. It provides a surface for cell migration during growth and wound healing.

A

Basement Membrane

129
Q

What are the 3 types of layering in epithelial tissue?

A

1) Simple
2) Pseudostratified
3) Stratified

130
Q

A type of layering in epithelial tissue that is one layer and good for passage of substances.

A

Simple

131
Q

A type of layering in epithelial tissue that is a single layer where not all cells reach the free surface. Some have cilia and goblet cells.

A

Pseudostratified

132
Q

What are the 3 shapes in epithelial tissue?

A

1) Squamous
2) Cuboidal
3) Columnar

133
Q

A type of shape in epithelial tissue that is flat and thin. Helps with rapid movement of substances or protection depending on the layering.

A

Squamous

134
Q

A type of shape in epithelial tissue that is cube or hexagon shaped. Free surface may have microvilli that are good for secretion/absorption.

A

Cuboidal

135
Q

A type of shape in epithelial tissue that is taller than wide. Free surface may have cilia or microvilli that are good for secretion/absorption.

A

Columnar

136
Q

One or more cells that make and secrete a particular product.

A

Gland

137
Q

What are the 2 kinds of glands?

A

1) Exocrine
2) Endocrine

138
Q

A type of gland that secretes their products into ducts (tubes) that empty onto the epithelial surface.

A

Exocrine Glands

139
Q

A type of gland that secretes their products into the interstitial fluid and diffuse directly into the bloodstream without flowing through a duct.

A

Endocrine Glands

140
Q

A tissue made of extracellular matrix and cells that function as protection, support, binding, transportation, energy and immunity. Most have good blood and nerve supply.

A

Connective Tissue

141
Q

Contains protein fibres and ground substance.

A

Extracellular Matrix (ECM)

142
Q

What are the 3 types of protein fibres?

A

1) Collagen
2) Elastin
3) Reticular

143
Q

A protein fibre that is white, very strong and resists tensile forces.

A

Collagen

144
Q

A law in which the arrangement of fibres is determined by the forces acting on them.

A

Wolff’s Law

145
Q

A protein fibre that is yellow, smaller than collagen and strong but stretchy.

A

Elastin

146
Q

A protein fibre that is thin, fine collagen fibres that form branching networks.

A

Reticular

147
Q

A type of layering in epithelial tissue that is more than one layer and is good for protection.

A

Stratified

148
Q

May be fluid, gel-like or calcified and it supports the cells and through it. Substances are exchanged between the blood and the cells.

A

Ground Substance

149
Q
A
150
Q

Some different types of __________ tissue cells are:
- Blasts
- Macrophages
- Plasma cells
- Mast cells
- Adipocytes

A

Connective

151
Q

A type of connective tissue cell that helps to make something. Each major type of connective tissue contains these cells.

A

Blasts

152
Q

A type of blast cell that is found in loose and dense connective tissue. They make collagen, elastin and reticular fibres.

A

Fibroblasts

153
Q

A type of blast cell that helps to make bone.

A

Osteoblasts

154
Q

A type of blast cell that helps to make cartilage.

A

Chondroblasts

155
Q

A type of connective tissue cell that eats harmful bacteria and cleans up cellular debris.

A

Macrophages

156
Q

A type of connective tissue cell that is part of the immune response and secretes antibodies to protect you from invaders.

A

Plasma Cells

157
Q

A type of connective tissue cell that makes histamine, which is part of the inflammatory response.

A

Mast Cells

158
Q

A type of connective tissue cell that stores fat.

A

Adipocytes

159
Q

Some different types of __________ tissue are:
- Loose
- Dense
- Bone
- Cartilage
- Liquid

A

Connective

160
Q

A type of connective tissue that has more cells and fewer fibres, which are loosely intertwined.

A

Loose

161
Q

What are the 3 types of loose connective tissue?

A

1) Areolar
2) Adipose
3) Reticular

162
Q

A type of loose connective tissue that is the most widely distributed connective tissue in the body. Its functions include strength, elasticity and support.

A

Areolar

163
Q

A type of loose connective tissue that contains a lot of adipocytes and is located beneath the skin/around some organs. Its functions include thermoregulation, energy, support and protection.

A

Adipose

164
Q

A type of loose connective tissue that is located in structures that have a filtering component (e.g. liver, spleen, lymph nodes). Forms the supporting framework of organs, binds smooth muscle cells and filters/removes old blood cells and microbes.

A

Reticular

165
Q

A type of connective tissue that has fewer cells and more fibres that are mostly collagen.

A

Dense

166
Q

What are the 3 types of dense connective tissue?

A

1) Regular
2) Irregular
3) Elastic

167
Q

A type of dense connective tissue in which collagen is arranged in parallel patterns. It is located in tendons and most ligaments. Functions include being very strong but pliable.

A

Regular

168
Q

A type of dense connective tissue in which collagen is arranged in random patterns. It is located in areas needing structure/support, as well as areas subject to many forces.

A

Irregular

169
Q

A type of dense connective tissue in which there is a high elastin content contributing to stretchiness. It is located in lung tissue, arteries and ligaments between vertebrae.

A

Elastic

170
Q

A type of connective tissue that has fewer cells with large amounts of collagen fibres. The matrix is filled with calcium phosphate salts, making it very hard. Function as protection, support and movement.

A

Bone (aka. Osseous Tissue)

171
Q

A type of connective tissue that is strong and resilient. The cells are called chondrocytes and the ground substance has large amounts of collagen and elastin. It is avascular and aneural.

A

Cartilage

172
Q

What are the 3 types of cartilage connective tissue?

A

1) Hyaline
2) Fibro
3) Elastic

173
Q

A type of cartilage connective tissue that is most common in the body, has a blue-white appearance when healthy and helps form articulations. Functions include flexibility, support and shock absorption.

A

Hyaline

174
Q

A type of cartilage connective tissue that is tougher, located between vertebrae (e.g. IVDs) and functions as support.

A

Fibro

175
Q

A type of cartilage connective tissue that has more elastin fibres, is part of the external ear for example and functions as support/flexibility while keeping shape.

A

Elastic

176
Q

A type of liquid connective tissue in which cells are surrounded by plasma and contain red & white blood cells, as well as platelets. Functions as a transport system.

A

Blood

177
Q

A type of liquid connective tissue that is a plasma-like fluid functioning in immunity, transportation and fluid regulation.

A

Lymph

178
Q

What are the 3 types of muscle tissue?

A

1) Skeletal
2) Smooth
3) Cardiac

179
Q

A type of muscle tissue that is striated, cells are long/cylindrical and the shape is defined by connective tissue. It also attaches to the skeleton (some attach to skin). Functions include movement and heat production. This tissue is under voluntary control.

A

Skeletal (aka. Striated Muscle)

180
Q

A type of muscle tissue that is found in the walls of hollow tubes, is under involuntary control and the cells are spindle shaped. Functions include constriction of tubes and movement of substances through tubes.

A

Smooth

181
Q

A type of muscle tissue that is branched striated fibres that fit together tightly. They are under involuntary control and functions include blood flow/propulsion.

A

Cardiac

182
Q

What are the 2 types of nervous tissue cells?

A

1) Neuroglia
2) Neurons

183
Q

A nervous tissue cell that supports, nourishes and protects the nervous system.

A

Neuroglia

184
Q

A nervous tissue cell that is the communicative portion of the nervous system.

A

Neuron (aka. Nerve Cell)

185
Q

Part of a neuron that has multiple or single extensions off the cell body and functions as the input portion.

A

Dendrite

186
Q

A part of a neuron that contains the nucleus and other organelles. It is known as the “control centre” and carries out the cell processes (e.g. protein synthesis).

A

Cell Body (aka. Soma, Perikaryon)

187
Q

Part of a neuron that is a thin cylindrical process off the cell body. Functions as the output portion.

A

Axon