Top 50 Closeout Drugs Flashcards
Atorvastatin
Lipitor | Statin | Nausea/dyspepsia, myalgia, may increase enzyme levels during LFT (ask if follow-up is scheduled)
Take at night | Avoid grapefruit juice | Lifestyle modifications
*generally well tolerated
Lovastatin
Mevacor | Statin | Nausea/dyspepsia, myalgia, may increase enzyme levels during LFT (ask if follow-up is scheduled)
Take at night | Avoid grapefruit juice | Lifestyle modifications
*generally well tolerated
Pravastatin
Pravachol | Statin | Nausea/dyspepsia, myalgia, may increase enzyme levels during LFT (ask if follow-up is scheduled)
Take at night | Less reaction with grapefruit | Lifestyle modifications
*generally well tolerated
Simvastatin
Zocor | Statin | Nausea/dyspepsia, myalgia, may increase enzyme levels during LFT (ask if follow-up is scheduled)
Take at night | Avoid grapefruit juice
*generally well tolerated
Atenolol
Tenormin | Beta-blocker | Hypertension |
Exercise intolerance, sexual dysfunction, fatigue, depression, dizziness
Monitor HR/BP | do not discontinue abruptly | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
*let doctor know if you are feeling tired all of the time
Metoprolol Tartrate
Lopressor | Beta-blocker | Hypertension |
Exercise intolerance, sexual dysfunction, fatigue, depression, dizziness
Monitor HR/BP | do not discontinue abruptly | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
*let doctor know if you are feeling tired all of the time
Metoprolol Succinate
Toprol XL | Beta-blocker | Hypertension |
Exercise intolerance, sexual dysfunction, fatigue, depression, dizziness
Monitor HR/BP | do not discontinue abruptly | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
*let doctor know if you are feeling tired all of the time
Carvedilol
Coreg | Beta-blocker | Hypertension |
Exercise intolerance, sexual dysfunction, fatigue, depression, dizziness
Monitor HR/BP | do not discontinue abruptly | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
*let doctor know if you are feeling tired all of the time
Amlodipine
Norvasc | Calcium Channel Blocker | Hypertension| Edema, fatigue, constipation
Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Diltiazem
Cardizem, Dilacor, Tiazac | Calcium Channel Blocker | Hypertension| Edema, fatigue, constipation
Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Verapamil
Calan, Verelan | Calcium Channel Blocker | Hypertension| Edema, fatigue, constipation
Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Lisinopril
Zestril, Prinivil | ACE Inhibitor | Hypertension | Cough, dizziness, rarely angiodema
Monitor electrolytes | hypotension on first dose may be worse if dehydrated | Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Enalapril
Vasotec | ACE Inhibitor | Hypertension | Cough, dizziness, rarely angiodema
Monitor electrolytes | hypotension on first dose may be worse if dehydrated | Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Benazepril
Lotensin | ACE Inhibitor | Hypertension | Cough, dizziness, rarely angiodema
Monitor electrolytes | hypotension on first dose may be worse if dehydrated | Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Losartan
Cozaar | Angiotensin Receptor Blocker | Hypertension | Dizziness, angiodema (rare)
Monitor electrolytes | hypotension on first dose may be worse if dehydrated | Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Olmesartan
Benicar | Angiotensin Receptor Blocker | Hypertension | Dizziness, angiodema (rare)
Monitor electrolytes | hypotension on first dose may be worse if dehydrated | Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Hydrochlorothiazide
Hydrodiuril, Microzide | Thiazide diuretic | Hypertension | Urination, photosensitivity, rash
Monitor electrolytes | potassium wasting | Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Chlorthalidone
Hygroton | Thiazide diuretic | Hypertension | Urination, photosensitivity, rash
Monitor electrolytes | potassium wasting | Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Furosemide
Lasix | Loop diuretic | Hypertension | Urination, photosensitivity, rash
Monitor electrolytes | potassium wasting | Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Triamterene/hydrochlorothiazide
Maxzide, Dyazide | Potassium sparing diuretic | Hypertension | Urination, photosensitivity, rash
Monitor electrolytes | potassium sparing | Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Spironolactone
Aldactone | Potassium sparing diuretic | Hypertension | Urination, photosensitivity, rash
Monitor electrolytes | potassium sparing | Monitor BP/HR | dizziness | lifestyle modifications (weight, moderate alcohol, exercise, DASH diet, no smoking, low sodium)
Warfarin
Coumadin | Vitamin K Antagonist/Anticoagulant | Thrombosis/Embolism | INR too high you will bleed, too low you will clot
Consistent diet but avoid foods high in vitamin K | Avoid NSAIDs | Watch drug, food and herb interactions | keep ALL INR appointments
*Warfarin interacts with many drugs so encourage patient to talk to provider about any new medications at once
Clopidogrel
Plavix | Antiplatelet | Atrial Fibrillation | Increased risk of bleed, rash, pruritus
Avoid use with omeprazole (ask provider first)
Metformin
Glucophage | Biguanide | Type 2 Diabetes Mellitus | N/V, diarrhea, flatulence
Monitor AIC, renal function | lifestyle modifications | unlikely to cause hypoglycemia
*if side effects do not reside, talk with doctor about changing dosing
Regular Insulin
Humulin R, Novolin R | Insulin | Type 1 or 2 Diabetes Mellitus | Hypoglycemia, weight gain
Encourage home BG monitoring | Ensure patient knows what to do if hypoglycemic | Proper pen/vial technique and storage
*ask patient if they are aware of signs of low BG
Lispro
Humalog | Insulin | Type 1 or 2 Diabetes Mellitus | Hypoglycemia, weight gain
Encourage home BG monitoring | Ensure patient knows what to do if hypoglycemic | Proper pen/vial technique and storage
*ask patient if they are aware of signs of low BG
**rapid acting
Aspart
Novolog | Insulin | Type 1 or 2 Diabetes Mellitus | Hypoglycemia, weight gain
Encourage home BG monitoring | Ensure patient knows what to do if hypoglycemic | Proper pen/vial technique and storage
*ask patient if they are aware of signs of low BG
**rapid acting
Glargine
Lantus | Insulin | Type 1 or 2 Diabetes Mellitus | Hypoglycemia, weight gain
Encourage home BG monitoring | Ensure patient knows what to do if hypoglycemic | Proper pen/vial technique and storage
*ask patient if they are aware of signs of low BG
**long-acting (24hrs)
Cyclobenzaprine
Flexeril | Muscle relaxant | Dry mouth, hypotension, dizziness, sedation
Avoid other CNS depressants | Avoid abrupt withdrawal if taken regularly
*make sure patient knows to take only as needed
Tizanidine
Zanaflex | Muscle relaxant | Dry mouth, hypotension, dizziness, sedation
Avoid other CNS depressants | Avoid abrupt withdrawal if taken regularly
*make sure patient knows to take only as needed
Tramadol
Ultram | Analgesic | Pain | Sedation, constipation, risk of abuse
Abuse/dependence | Avoid other CNS depressants | Watch APAP max dosing (4000mg)
*not an opioid but acts like one
Oxycodone IR
OxyIR | Opioid Analgesic | Pain | Sedation, constipation, risk of abuse
Abuse/dependence | Avoid other CNS depressants | Watch APAP max dosing (4000mg)
Oxycodone CR
Oxycontin | Opioid Analgesic | Pain | Sedation, constipation, risk of abuse
Abuse/dependence | Avoid other CNS depressants | Watch APAP max dosing (4000mg)
Oxycodone/APAP
Percocet | Opioid Analgesic | Pain | Sedation, constipation, risk of abuse
Abuse/dependence | Avoid other CNS depressants | Watch APAP max dosing (4000mg)
Hydrocodon/APAP
Norco, Lortab, Vicodin | Opioid Analgesic | Pain | Sedation, constipation, risk of abuse
Abuse/dependence | Avoid other CNS depressants | Watch APAP max dosing (4000mg)
Fentanyl Patch
Duragesic | Opioid Analgesic | Pain | Sedation, constipation, risk of abuse
Abuse/dependence | Avoid other CNS depressants | Watch APAP max dosing (4000mg)
- dispose in toilet after folding
- *do not use heating blankets or hot pads
- **exercise may increase absorption
- ***can shower with patch on
- **place on upper body, rotate sites
Fluoxetine
Prozac | SSRI | Depression | Nausea, headache, restlessness
Do not discontinue abruptly | AM or PM depending on how it affects individual patient (fluoxetine generally taken in AM) | can increase suicidal ideation | may take up to 6 weeks to see full effects | most cause sexual dysfunction
*potential increased risk of bleeds in those on anticoagulants
Paroxetine
Paxil | SSRI | Depression | Nausea, headache, restlessness
Do not discontinue abruptly | AM or PM depending on how it affects individual patient | can increase suicidal ideation | may take up to 6 weeks to see full effects | most cause sexual dysfunction
*potential increased risk of bleeds in those on anticoagulants
Sertralien
Zoloft | SSRI | Depression | Nausea, headache, restlessness
Do not discontinue abruptly | AM or PM depending on how it affects individual patient | can increase suicidal ideation | may take up to 6 weeks to see full effects | most cause sexual dysfunction
*potential increased risk of bleeds in those on anticoagulants
Citalopram
Celexa | SSRI | Depression | Nausea, headache, restlessness
Do not discontinue abruptly | AM or PM depending on how it affects individual patient | can increase suicidal ideation | may take up to 6 weeks to see full effects | most cause sexual dysfunction
*potential increased risk of bleeds in those on anticoagulants
Bupropion
Wellbutrin, Zyban (smoking cessation) | NE and Dopamine reuptake inhibitor | depression | dry mouth, insomnia, agitation, headache, weight loss, tachycardia
Do not discontinue abruptly | AM or PM depending on how it affects individual patient | can increase suicidal ideation | may take up to 6 weeks to see full effects
Less sexual dysfunction | CI in seizure disorder (if taking over 300mg)
Venlafaxine
Effexor | SNRI | Depression | HTN, increased sweating as result of HTN
Titrate to minimize SE | Do not discontinue abruptly | AM or PM depending on how it affects individual patient | can increase suicidal ideation | may take up to 6 weeks to see full effects | increased risk of bleeding in those taking anticoagulant
Lorazepam
Ativan | Benzodiazepine | Anxiety | anterograde amnesia, somnolence/dizziness, abuse/withdrawal
Avoid other CNS depressants | if taken regularly, taper off slowly | prn
Alprazolam
Xanax | Benzodiazepine | Anxiety | anterograde amnesia, somnolence/dizziness, abuse/withdrawal
Avoid other CNS depressants | if taken regularly, taper off slowly | prn
Zolpidem
Ambien | Sedative/hypnotic | insomnia | daytime somnolence, dizziness, parasomnias
Take right before bed | plan for full 8 hours of sleep | potential dependence
Methylphenidate
Ritalin, Concerta | CNS stimulant | ADHD | Nausea, loss of appetite, insomnia/irritability, HA
Monitor BP/HR (height and weight for kids) | Potential for dependency and abuse | ask about follow-up appointments | patient will need new Rx for more
Amphetamine Salt Combination (Dextroamphetamine/Amphetamine)
Adderall | CNS stimulant | ADHD | Nausea, loss of appetite, insomnia/irritability, HA
Monitor BP/HR (height and weight for kids) | Potential for dependency and abuse | ask about follow-up appointments | patient will need new Rx for more
Gabapentin
Neurontin | Antiepileptic | Seizures | Drowsiness/sedation, dizziness, edema, ataxia, “fuzzy headed” at increased doses
Various indications | caution with other CNS depressants
Albuterol HFA
ProAir, Ventolin, Proventil | SABA | Asthma | HA, tremor, shakiness, tachycardia, lightheadedness
Instruct on inhalation technique | for rescue! | if using more than 2x/week reevaluate therapy
Fluticasone HFA
Flovent | Corticosteroid | Asthma | Thrush/URI, cough/hoarseness, HA
Rinse mouth after every use | use every day | instruct on proper inhalation technique
Fluticasone + Salmeterol
Advair | Corticosteroid + LABA | Asthma | Thrush/URI, cough/hoarseness, HA
Rinse mouth after every use | use every day | instruct on proper inhalation technique
Tiotropium
Spiriva Handihaler | Anticholinergic | COPD | Dry mouth, cough/hoarseness, bitter taste, URI
Instruct on proper technique
Ipratoprium/Albuterol
Combivent Respimat | Anticholinergic | COPD | Dry mouth, cough/hoarseness, bitter taste, URI
Instruct on proper technique
Prednisone
Deltasone | Oral Corticosteroid | Asthma/COPD | Insomnia/agitation, fluid retention, can increase BG and BP at high doses
Take early in the day | sometimes taper dose | typically take tablets together
Triamcinolone
Kenalog | Topical corticosteroid | Allergic rhinitis | skin atrophy, burning, contact dermatitis
Apply sparingly | do not occlude unless instructed to | do not use longer than 10-14 days to avoid AE (unless told otherwise)
Amoxicillin
Amoxil, Trimox | Beta-lactam | Infection
Beware of PCN allergy
Take how prescribed and finish whole course | may cause nausea and mild diarrhea; take with food to avoid | predisposed to yeast infection | may interact with oral contraceptives | c.dif risk - use probiotics
Amoxicillin w/ Clavulanate
Augmentin | Beta-lactam | Infection
Beware of PCN allergy | diarrhea more common
Take how prescribed and finish whole course | may cause nausea and mild diarrhea; take with food to avoid | predisposed to yeast infection | may interact with oral contraceptives | c.dif risk - use probiotics
Cephalexin
Keflex | Beta-lactam | Infection
Beware of PCN allergy
Take how prescribed and finish whole course | may cause nausea and mild diarrhea; take with food to avoid | predisposed to yeast infection | may interact with oral contraceptives | c.dif risk - use probiotics
Ciprofloxacin
Cipro | Fluoroquinolone | Infection | tendonopathy (Achilles), photosensitivity, peripheral neuropathy, QT prolongation
Avoid taking with antacids, multivitamins, and dairy products
Take how prescribed and finish whole course | may cause nausea and mild diarrhea; take with food to avoid | predisposed to yeast infection | may interact with oral contraceptives | c.dif risk - use probiotics
Doxycycline
Vibramycin | Tetracycline | Infection | Photosensitivity, rash
Not for those under 8 due to teeth yellowing | avoid taking mineral supplements and antacids within 2 hours of taking | take with plenty of water, can upset stomach
Take how prescribed and finish whole course | may cause nausea and mild diarrhea; take with food to avoid | predisposed to yeast infection | may interact with oral contraceptives | c.dif risk - use probiotics
Clindamicin
Cleocin | Lincosamide | Infection | NVD
Take how prescribed and finish whole course | may cause nausea and mild diarrhea; take with food to avoid | predisposed to yeast infection | may interact with oral contraceptives | c.dif risk - use probiotics (DO NOT recommend loperamide)
Azithromycin
Zithromax | Macrolide | Infection | QT prolongation, GI upset
Take with or without food | Do not take with antacids
Take how prescribed and finish whole course | may cause nausea and mild diarrhea; take with food to avoid | predisposed to yeast infection | may interact with oral contraceptives | c.dif risk - use probiotics
Sulfamethoxazole/Trimethoprim
Bactrim, Septra | Sulfonamide | Infection | Photosensitivity, rash
Drink lots of floods to avoid crystalluria | potential allergy
Take how prescribed and finish whole course | may cause nausea and mild diarrhea; take with food to avoid | predisposed to yeast infection | may interact with oral contraceptives | c.dif risk - use probiotics
Polyethylene Glycol
GoLytely | Bowel prep osmotic laxative | prior colonoscopy | diarrhea, nausea, increased thirst
Avoid dark colors | do not plan to leave house | read packet of info from prescriber | product only good for 48 hours once water added
Latanoprost
Xalatan | Prostanoid receptor agonist | elevated intraocular pressure | mild irritation, blurred vision, eyelash growth, iris color change
Show patient how to administer; qd pm
Tobramycin
Tobrex | Aminoglycoside antibiotic | Ocular infection | mild irritation, blurred vision
Counsel on administration technique
Gentramicin
Gentak | Aminoglycoside antibiotic | Ocular infection | mild irritation, blurred vision
Counsel on administration technique
Erythromycin
Romycin, Ilotycin | Aminoglycoside antibiotic | Ocular infection | mild irritation, blurred vision
Counsel on administration technique (ointment)
Ethinyl Estradiol/Norgestimate
Oral contraceptive | breast tenderness, weight gain, HA/migraine, increased clot risk
Take every day | if miss 2, see insert | start first day of menstrual cycle | no smoking
Ethinyl Estradiol/levonorgestrel
Amethia, Oral Orsythia, Lutera | contraceptive | breast tenderness, weight gain, HA/migraine, increased clot risk
Take every day | if miss 2, see insert | start first day of menstrual cycle | no smoking
Ethinyl Estradiol/norethindrone
Oral contraceptive | breast tenderness, weight gain, HA/migraine, increased clot risk
Take every day | if miss 2, see insert | start first day of menstrual cycle | no smoking
Ethinyl Estradiol/drosperinone
Zarah, Ocella, Yasmin, Yaz | Oral contraceptive | breast tenderness, weight gain, HA/migraine, increased clot risk
Take every day | if miss 2, see insert | start first day of menstrual cycle | no smoking
Acyclovir
Zovirax | Antiviral | Herpes, Varicella | up to 5x/day | malaise, headache, NVD
Works best at first sign of outbreak | fluid intake | with or without food
Valacyclovir
Zovirax | Antiviral | Herpes, Varicella, HIV | bid-tid | malaise, headache, NVD
Works best at first sign of outbreak | fluid intake | with or without food
Alendronate
Fosamax | bisphosphonate | 1x/week for osteoporosis | NV, heartburn, atypical femur fracture (rare) and osteonecrosis of jaw (rare)
Take on empty stomach with full glass of water in morning | avoid lying down for 30 minutes (heartburn) | calcium and vitamin D
Levothyroxine
Synthroid, Levoxyl | Thyroid hormone replacement | no SE if euthyroid; if dose too high, tachycardia, sweating and weight loss
Take on empty stomach | monitor TSH | take in morning
Tamsulosin
Flomax | Alpha-blocker | BPH | dizziness, orthostatic hypotension, fatigue, HA
Monitor BP
Sildenafil
Viagra | Phosphodiesterase-5 inhibitor | ED | HA, flushing, color vision change, dyspepsia, priapism
CI with nitrates | limit 1 dose/day
Vardenafil
Levitra | Phosphodiesterase-5 inhibitor | ED | HA, flushing, color vision change, dyspepsia, priapism
CI with nitrates | limit 1 dose/day
Tadalafil
Cialis | Phosphodiesterase-5 inhibitor | ED | HA, flushing, color vision change, dyspepsia, priapism
CI with nitrates | limit 1 dose/day
*take 30-60 minutes prior to sex
Epinephrine Pen
EpiPen, Adrenaclick, AuviQ | Epinephrine
Tell patients to get comfortable with technique | still need to seek medical attention | always keep on hand and check expiration date