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809 - Exam Block 2 > Tooth Development - Rougier > Flashcards

Tooth Development - Rougier Flashcards

1
Q

Arch 1 is innervated by CN

A

V

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2
Q

arch 2 is innervated by CN

A

VII

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3
Q

During the _____ week of development thickenings of oral epithelium develop, overlying the future dental arches in the upper and lower jaws

A

6th

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4
Q

The dental lamina lies _______ (in coronal section) to the vestibular lamina; it has a horseshoe shape in its entirety

A

medial

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5
Q

The buds plus the closely-associated ectomesenchyme represent the primordia of the ________ teeth

A

deciduous

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6
Q

All the buds are present by the _____ week

A

8th

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7
Q

Development of cells that form dental tissues is the process of

A

histodifferentiation

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8
Q

At what month in development does the cap-like configuration

A

3rd

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9
Q

The cap-shaped epithelial proliferation is now identified as the _________ which has/forms what 4 things?

A

enamel organ

  1. inner enamel epithelium
  2. outer enamel epithelium
  3. SR
  4. SI
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10
Q

The enamel organ is _______ and lacks ________

A

avascular ; innervation

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11
Q

what is responsbile for formation of enamel

A

the enamel organ

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12
Q

the ______ is a condensation of ectomesenchymal tissue lying within the concavity of the enamel organ

A

dental papilla

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13
Q

once dentinogenesis is initiated, the dental papilla will become

A

vascularized and innervated

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14
Q

the cells of the dental papilla give rise to _____ and _____

A

dentin ; pulp

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15
Q

The ______ is a thickening of
ectomesenchymal tissue that encompasses the enamel
organ and dental papilla

A

dental follicle (or sac)

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16
Q

the dental follicle (sac) gives rise to what 3 things

A

cementum
PDL
alveolar bone

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17
Q

Cells of the inner enamel epithelium become tall
columnar cells. They are on their way to becoming
enamel-producing cells, the

A

ameloblasts

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18
Q

until production of enamel begins, you should actually view ameloblasts as what?

A

preameloblasts

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19
Q

In their preameloblast stage the inner enamel epithelial
cells induce neighboring ectomesenchymal cells of the
dental papilla to differentiate into dentin producing cells,
the ______

A

odontoblasts

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20
Q

we see development of the tooth buds for the permanent teeth, excluding the _____ in the _____ stage

A

molars ; bud

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21
Q

Because the molars don’t have decidious predecessors, the the tooth buds for permanent molars develop from

A

posterior extensions of the dental lamina

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22
Q

during the bell stage, the cells of the ____________ begin to degenerate. Over time,
this will create a furrow that forms the

A

vestibular lamina ; oral
vestibule

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23
Q

Dentinogenesis begins in the occlusal region of the future crown, where the newly differentiated odontoblasts produce

A

predentin

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24
Q

Predentin is the ___ matrix of dentin

A

organic

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25
Q

Mineralization of predentin forms ____ which encloses
the cytoplasmic process in a ______

A

dentin ; dentinal tubule

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26
Q

As the odontoblasts migrate centrally, a layer of predentin will ______ be present

A

always

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27
Q

enamel formation begins with mineralization of

A

dentin

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28
Q

preameloblasts are induced to complete their differentiation into ameloblasts by the
presence of

A

mineralized dentin

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29
Q

The simultaneous formation of enamel and dentin
is termed the _____ stage

A

appositional

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30
Q

As preameloblasts
differentiate, they induce differentiation of _______
and _______

A

odontoblasts ; dentinogenesis

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31
Q

dentinogenesis induces
completion of the differentiation of _______ and
_______

A

ameloblasts ; amelogenesis

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32
Q

The dynamics of dentin and enamel formation are an example of

A

reciprocal induction

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33
Q

Once enamel formation achieves its definitive thickness the ameloblasts regress. They combine with the other layers of the enamel organ to form a protective cellular coating known as the

A

reduced enamel epithelium

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34
Q

Crown formation for deciduous teeth is completed during the year

A

first

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35
Q

The root of the tooth is comprised of

A

dentin

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36
Q

cells of the inner enamel epithelium will also induce differentiation of _____ for root formation

A

odontoblasts

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37
Q

neural crest cells migrate into the pharyngeal arches and mix with mesenchyme to produce ______ to help form teeth

A

ectomesenchyme

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38
Q

what is the embryonic period

A

fertilization through 8 weeks

39
Q

Initiation is signaled by development of the

A

dental lamina

40
Q

a thickening of oral epithelium overlying ectomesenchyme

A

dental lamina

41
Q

the _________ segment gives rise to maxillary incisors

A

intermaxillary

42
Q

what is the forerunner of the dental and vestibular lamina

A

the primary epithelial band

43
Q

developmental origin of oral epithelium is

A

ectoderm

44
Q

what line separates ectoderm from ectomesenchyme (which has NCCs)

A

the primary epithelial band

45
Q

differentiation of the primary epithelial band proceeds differentiation of

A

ectomesenchyme

46
Q

what are the 6 events associated with tooth development

A

Initiation
Proliferation
Morphogenesis
Differentiation
Apposition
Eruption

47
Q

what event associated with tooth development is:

dental lamina formation

A

initation

48
Q

what event associated with tooth development is:

mitosis within dental lamina &
ectomesenchyme to establish tooth primordium

A

proliferation

49
Q

what event associated with tooth development is:

changes of shape that lead to bud, cap, bell stages

A

Morphogenesis

50
Q

what event associated with tooth development is:

formation of ameloblasts & odontoblasts

A

Differentiation

51
Q

what event associated with tooth development is:

dentin & enamel formation

A

Apposition

52
Q

what event associated with tooth development is:

root formation

A

eruption

53
Q

the vestibular lamina is ALWAYS ______ to the dental lamina

A

labial

54
Q

formation of dental lamina is also mirrored by the 2nd folding that is labial to it and called a

A

vestibular lamina

55
Q

a thickening of oral epithelium (derived from ectoderm)

A

dental lamina

56
Q

change of the plane of cleavage in cells of the epithelial band is the origin of the

A

dental lamina

57
Q

tooth buds are derived from

A

ectoderm

58
Q

tooth bud formation happens during the __ to __ week of development

A

6th - 8th

59
Q

_______ tissue releases factors that stimulate development of
the tooth bud

A

Ectomesenchymal

60
Q

The tooth bud becomes the enamel organ in the ____ stage

A

cap

61
Q

the enamel organ has _____ origin

A

ectodermal

62
Q

dental papilla is derived from ______ and “makes” ____ and _____

A

ectomesenchyme ; pulp ; dentin

63
Q

dental follicle is derived from ______ and “makes” ____ , _____ , and _____

A

ectomesenchyme ; PDL ; cementum ; alveolar bone

64
Q

The vestibular lamina lies ____ to the cap stage

A

lateral

65
Q

the _______ is the beginning of all tooth cusps

A

enamel knot

66
Q

the origin of all dental tissue is the

A

cervical loop

67
Q

3 Important Events during the Bell Stage:

A

Configuration of the crown is determined

a successional lamina is formed, with permanent tooth buds

histodifferentiation: dentin and enamel formation will occur

68
Q

formation of crown is determined during the _____ stage

A

bell

69
Q

we have the beginning of our appositional stage during what stage

A

Bell

70
Q

the sucessional lamina is always on the ____ side

A

lingual

71
Q

during the late bell stage, the dental lamina will begin to atrophy internally and disconnect from the oral epithelium and develop a 2nd process called the

A

successional lamina

72
Q

the successional lamina gives rise to

A

permanent dentition

73
Q

10 primary teeth and 10 permanent teeth will develop in association with the initial

A

dental lamina

74
Q

______ are first to mature and erupt

A

Incisors

75
Q

Odontogenesis moves ______ as jaws develop and lengthen

A

posteriorly

76
Q

In the bell stage, the configuration of the crown is
determined in sites where _______ ceases and causes buckling of the _____

A

mitotic activity ; IEE

77
Q

There is histodifferentiation of cells of the IEE and Outer Dental Papilla (ODP) in

A

future cuspal area

78
Q

Cells of the IEE begin organizing to form

A

preameloblasts

79
Q

cells in IEE secrete growth factor that secrete into cells of the outer dental papilla which causes them to differentiate into odontoblasts which secrete

A

dentin

80
Q

ameloblasts secrete a ________ matrix which eventually becomes ______

A

non-mineralized ; mineralized

81
Q

what is the only tissue with a non-mineralized precursor

A

enamel

82
Q

_______ are the first cells to reach functional maturity

A

Odontoblasts

83
Q

the location of future cuspal edge is found in what stage

A

bell stage

84
Q

1st tissue secreted by odontoblasts is _______ and the 1st mineralized tissue they secrete is _________ which begins in the _____ until it reaches the ________ and the ______ and then it is complete

A

pre-dentin ; dentin ; cusp ; cervical loop ; crown

85
Q

Appositional stage begins in _____ regions and progresses in a cervical direction

A

cuspal

86
Q

The interface where enamel and dentin meet is termed the _____

A

DEJ

87
Q

Ameloblasts move _____ from the DEJ as enamel is formed

A

away

88
Q

Odontoblasts migrate _____ developing pulp

A

into

89
Q

Dentin and enamel formation extend in a ______ direction

A

cervical

90
Q

Enamel formation stops when it reaches the

A

cervical loop

91
Q

the enamel organ has NO _________

A

blood supply

92
Q

When the full thickness of the enamel is achieved, the layers
of the enamel organ become compressed, forming the

A

reduced enamel epithelium

93
Q

The REE also has as protective mechanism, separating the ______ from the _______

A

enamel ; ectomesenchyme

809 - Exam Block 2 (14 decks)

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