Salivary Glands - Krimm Flashcards
salivary glands are _______ glands
exocrine
3 major salivary glands
parotid gland
submandibular
sublingual
5 minor salivary glands
Von Ebner’s gland (posterior tongue)
Labial
Palatal
Buccal
Lingual
Blood vessels in the stroma supply
parenchyma
nerve fibers in the stroma supply
parenchyma
plasma cells in the stroma secrete
antibodies
fibroblasts in the stroma secrete
collagen
fat cells in the stroma increase with
age
autonomic nervous system controls _______ glands
salivary
salivary gland nerve supply is from _____ and ______ sources
sympathetic and parasympathetic
salivary glands don’t have synapses, instead they have lots of __________ associated with the gland that helps the glands stimulate more saliva
unmyelinated nerve endings
what is the part of the salivary gland that actually produces saliva
parenchyma
what 3 acini do parenchyma have
serous
mucous
mixed
the parotid gland contains what kind of acini
serous
some minor salivary glands contain what kind of acini
mucous
submandibular and sublingual glands contains what kind of acini
mixed
what 3 ducts do parenchyma have
intercalated
striated
excretory
myoepthelial cells of acini have actin and myosin that squeeze the acinus to cause what
ejection of saliva
What kind of cell:
Pyramidal shape
Resting on basal lamina
Short, irregular microvilli
Exhibit many characteristics of polarized, protein secreting cells
Joined by zona occludens,
desmosomes, gap junctions
serous cell
What kind of cell?
Cuboidal to columnar
Oval nuclei pressed toward the base
Arranged in tubules around a central lumen
May or may not be accompanied by a serous demilune
mucous cell
What kind of cell?
Found surrounding the acini but within the basal lamina
Highly branched cells
Also associated with tubules; these are spindle shaped and lie parallel to the length of the duct
Myoepithelial cells
what order does fluid flow through ducts
intercalated ducts –> striated ducts
–> excretory duct –>
What kind of duct?
Smallest duct
Several acini drain into intercalated duct
Cuboidal epithelium
Adds specific proteins and water to saliva
Round nucleus that fills most of the cell
intercalated
What kind of duct?
Longer and more active duct
Site of reabsorption
- Against concentration gradient
- Requires energy (ATP)
- Converts isotonic (primary saliva
to hypotonic fluid (secondary
saliva)
Highly polarized
- short microvilli to increase SA
- numerous infoldings of
basolateral membrane (striations)
- vertically aligned mitochondria
striated ducts
What kind of duct?
Lacks striations
Series of connecting ducts becoming progressively wider
Moves from single epithelial layer to stratified epithelium
Lumen
Irregularly spaced nuclei
Often in septa; surrounded by fibroblasts
Excretory Duct
Capillaries provide
water
fluid from capillaries empties in and cells take it up which produces
water
primary saliva is formed by what cells
secretory
secretory cells add/produce _____ to saliva
proteins/glycoproteins
secretion is regulated by
secretory granules/vesicles
unstimulated salivary glands are full of
zymogen granules
plasma cells produce
antibodies
secretory cells have receptors that will bind to the _______ and pass them into the saliva
antibodies
primary saliva is produced by _____ and becomes secondary when it goes through ______
acini ; ducts
primary secretion - acini - h2o ________
permeable
secondary secretion - duct - h2o __________
impermeable
secretion in ______ and reabsorption along the ______
acini ; ducts
ducts modify saliva by changing the amounts of ___ and ____
Na+ and K+
primary saliva goes from _____ to ______ as it passes through the duct system
hypertonic to hypotonic
parotid is all _____. glands
serous
submandibular is mostly ____ with some _____
serous ; mucus
sublingual is mostly ____ with some _____
mucus ; serous
von Ebner’s glands are purely _______ and are found only in _______ glands
serous ; minor salivary
