Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

oral biology > tooth development > Flashcards

tooth development Flashcards

You may prefer our related Brainscape-certified flashcards:
AP® Biology flashcards Biology 101 flashcards
1
Q

What is initiation?

A

induction of tooth development

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is morphogenesis?

A

determination of tooth type

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is histogenesis?

A

differentiation of cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

From what embryological structure does oral epithelium derive?

A

first branchial arch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What determines fate of neural crest derived ectomesenchymal cells?

A
  1. area cells migrate to
  2. combination of homeobox gene expression
  3. Oral epithelium commits mesenchyme to tooth development
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which cells take control of later events in tooth development (tooth specificity)?

A

ectomesenchymal cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which transcription factor is KEY in the initiation of tooth development?

A

PITX2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what produces PITX2?

A

Oral epithelium (only)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the role of Shh?

A

Interacts with Wnt/7b to increase cell proliferation. increased expression =hyperdontia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is required for progression from bud stage of development?

A

PAX-9 and msx1 gene proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what type of stem cells are neural crest cells?

A

pluripotent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which cells take over control of tooth development after initiation stage?

A

ectomesenchymal cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is odotontogenic homeobox gene expression?

A

different combination of genes determine what type of tooth will form (molar, incisor, premolar, canine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

At what week in foetal development does tooth development start?

A

week 6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How does tooth bud form?

A

thickening of overlying oral epithelium, invaginates down in to underlying mesenchyme to form bud attached to oral epithelium via dental lamina`

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what does invagination of oral epithelium divide in to?

A

lingual dental lamina (future tooth) and buccal vestibular lamina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the fate of the buccal vestibular lamina?

A

forms space between inner cheek and buccal mucosa of gingivae.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What happens in the bud stage?

A
  1. condensation of surrounding ectomesenchymal cells

2. enamel organ forms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Around what week does CAP stage occur?

A

week 11/12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are the features of CAP stage?

A
  1. greater Histo and morphogenesis
  2. formation of inner and outer epithelium
  3. Stellate reticulum
  4. dental follicle and dental papilla become two defined regions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

how many layers of enamel organ in CAP stage?

A

3 layers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What layer is not present in CAP stage?

A

stratum intermedium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are the fate of cells in dental follicle?

A

cementoblasts, fibroblasts and osteoblasts

24
Q

What is a feature of bell stage?

A

formation on stratum intermedium

25
Q

At what stage does enamel organ break away from oral epithelium?

A

bell stage when dental lamina disintergrates

26
Q

What is the enamel knot?

A

At cusp tip or incisal edge, collection of signalling molecules in CAP stage

27
Q

What is the enamel cord?

A

Line of cells dividing stellate reticulum in to two, bell stage.

28
Q

At what point does the inner dental enamel epithelium stop proliferating?

A

when crown attains its final shape

29
Q

What are epithelial pearls of serres?

A

remnants of disintegrated dental lamina

30
Q

what happens at the end of bell stage?

A

start of enamel and dentine formation

31
Q

Which hard tissue starts forming first?

A

dentine first then enamel

32
Q

which cells produce pax-9?

A

ectomesencymal cells

33
Q

what triggers differentiation of odontoblasts?

A

signalling from pre-ameloblasts

34
Q

which cells contact when basal lamina breaks down?

A

pre-ameloblasts and odontoblast

35
Q

what causes differentiation from pre-ameloblasts to ameloblasts?

A

predentine

36
Q

what are the 5 stages of amelogenesis?

A
  1. pre-secretary
  2. secretary
  3. transition
  4. maturation
  5. post maturation
37
Q

what happens in the pre-secretary stage?

A
  1. resorption of basal lamina
  2. pre-ameloblasts become polarised columnar cells (ameloblasts)
  3. proximal terminal web forms
    4
38
Q

what happens in secretary stage?

A
  1. secretion of enamel proteins (amelogenins)
  2. Tomes process forms (delayed)
  3. further secretion and start of mineralisation simultaneously
  4. distal terminal web forms to adhere cells and control substances going in and out for mineralisation.
  5. tomes process retracts
  6. secretion finishes
39
Q

What are the cross striations of enamel presenting?

A

daily increments of enamel

40
Q

What are striae of retzius?

A

weekly increments of ennamel, running obliquely

41
Q

What occurs in the transition stage?

A
  1. Ameloblasts shrink to cuboidal cells
  2. 50% ameloblasts die
  3. Most enamel matrix removes
  4. basal lamina reforms
42
Q

What occurs in mineralisation?

A
  1. HA crystallites thicken and widen
  2. Reduced space between crystals
  3. Calcium, phosphate and carbonate brought in by ameloblasts (ruffle ended).
  4. Removal of water and degraded protein (smooth ended)
43
Q

What happens in post maturation stage?

A
  1. Ameloblasts flatten
  2. layers of enamel organ degenerate and reduced enamel epithelium and primary enamel cuticle form.`
  3. tooth erupts
  4. saliva =further mineralisation
44
Q

What is different about secretion of dentine?

A

There is a ‘pre’ unmineralised layer that always precedes the mineralised layer

45
Q

What is found in the dentine matrix?

A

collagen type 1, proteoglycans, glycoproteins, DPP

46
Q

the initial formation of odontoblasts forms two cell types, what are they?

A

differentiated odontoblast and undifferentiated ectomesenchymal cells (which will act as odontoblast reserve for later in life tertiary dentine)

47
Q

what lies in the dentinal tubules?

A

odontoblast process

48
Q

Where is hyper mineralised dentine found?

A

intra tubular dentine

49
Q

What is translucent dentine?

A

occurs when tubules are completely filled with calcified material

50
Q

How many odontoblasts per tubule?

A

one

51
Q

What is mantle dentine?

A

first dentine laid down in coronal region. found just below ADJ.

52
Q

What is difference about composition of mantle dentine?

A

type 1 collagen
less mineralised
fibres at 90 degrees to ADJ

53
Q

Where is circumpulpal dentine?

A

Around the pulp. regular dentine.

54
Q

What are the two types of tertiary dentine?

A

reactive (mild) and reparative (severe)

55
Q

When does root development commence?

A

when crown formation completes

oral biology (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions