ageing and dentistry Flashcards
when does intrinsic ageing of skin begin?
mid 20s
what are the features of intrinsic ageing?
collagen turnover slowed elastin less elastic benign neoplasms dry/pale fine wrinkles loss of fat/hollowing dont sweat loss of ECM less melanocytes more metalloproteinases less fibroblasts less blood supply
what are the histological features of histological features of extrinsic ageing?
abnormal elastic material (dermal elastosis)
collagen degeneration
malignant changes
inflam cells in dermis
what is the end result of skin ageing?
decreased wound healing
oxidative damage= increased malignancy risk
at what age does muscle start to be lost?
age 40
Describe the structural changes of alveolar bone with ageing?
surface become jagged with irregular sharpy fibres
increased mandibular mineralisation in some patients
what are the oral manifestations of systemic osteoporosis?
decreased mineral density in mandible
changes in cortex
increased severity of ridge resorption
increased missing teeth
which salivary gland is least likely to be affected by ageing?
parotid
What are the histological features of ageing salivary glands?
reduction in secretory proteins reduction of mucins more fibrous and fatty tissue lymphocyte infiltrate decreased secretory visicles
What are the features of ageing mucosa?
fragile, thin, less keratinised, changes in collagen, reduced wound healing, less elastic, fordyce spots
What are the feature of ageing tongue?
dorsal and lateral thinning of epithelium
fibrosis
increased collagen
defective signalling from taste buds`
what factors lead to an increase in mucosal lesions associated with ageing?
fragile mucosa, salivary gland problems, immunocompramised, increased autoimmune responses
what are the features are PDL ageing?
collagen fibrosis
less mobile teeth!
decreased cellularity
increased fat cells
