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Oral Bio II > Tooth development > Flashcards

Tooth development Flashcards

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Biology 101 flashcards
1
Q

What are the two layers that guide organogenesis

A

It is the epithelial-mesenchymal interactions (reciprocity)

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2
Q

Name 4 things that develop from the cranial neural crest cells?

A

Dentin, Pulp, Cementum, and Periodontal ligaments

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3
Q

What is the first thing you see in tooth development?

A

A thickening of the epithelium called the primary band

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4
Q

Which direction does the primary band grow?

A

Downward towards the ectomesenchyme

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5
Q

What are dental placodes?

A

They mark the places for future tooth development

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6
Q

Next to the dental lamina there is another lamina, what is it?

A

The vestibular lamina

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7
Q

What are the 6 steps in crown development?

A

Initiation, bud, cap, bell, apposition, and maturation

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8
Q

What does the ectomesenchyme come from?

A

Cranial neural crest cells

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9
Q

What provides the shape of the developing tooth?

A

There is cell proliferation at different locations and at different rate

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10
Q

During what two stages is the epithelium in control of what is happening?

A

Primary epithelial band and bud stage

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11
Q

In what stage does the inductive influence change over to the mesenchyme?

A

In the cap stage

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12
Q

What are the 4 layers that make up the enamel organ?

A

OEEs, stellate reticulum, stratum intermedium, and IEEs. These are all present in the bell stage

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13
Q

What is the stellate reticulum and the stratum intermedium rich in?

A

GAGs and Alkaline Phosphatase respectively

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14
Q

What makes up the tooth germ?

A

enamel organ, dental papilla, and the dental sac

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15
Q

Where does the successional dental lamina grow?

A

Always on the lingual side

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16
Q

What is an enamel knot?

A

It is a structure that is located in the enamel organ and tells the cells to slow/stop dividing. So they give shape to the developing tooth and their formation is controlled by the mesenchyme

17
Q

What is another name for the dental sac?

A

Dental follicle

18
Q

What makes up the cervical loop?

A

OEEs and IEEs. It is where they meet and is the future sight of the CEJ

19
Q

What is the function of the OEEs?

A

They form a protective barrier for the enamel organ

20
Q

What is the function of the stellate reticulum?

A

They support enamel production

21
Q

What is the function of the stratum intermedium?

A

Supports enamel mineralization (alkaline phosphatases)

22
Q

What is the function of the IEEs?

A

They become ameloblasts-enamel forming cells

23
Q

What is the order of reciprocal induction in the crown development in the apposition stage?

A

Enamel knots are formed, the slowing of proliferation caused IEEs to differentiate into preameloblasts, this then causes the outer dental papilla cells to organize and differentiate into preodontoblasts followed by odontoblasts. They then lay down pre-dentin which causes the preameloblasts to become ameloblasts which then lay down enamel.

24
Q

What are Tome’s processes?

A

They are like odontoblast processes but in enamel and they get mineralized.

25
Q

When does the DEJ form?

A

After the basement membrane disintegrates between the ameloblasts and odontoblasts

26
Q

How is dentin and enamel played down?

A

In layers (waves) like the rings on a tree

27
Q

When is the REE (reduced enamel epithelium) formed?

A

After complete maturation of the enamel

28
Q

What make up the REE?

A

It is the IEEs, OEEs, and what is left from the other two layers

29
Q

What is the initial layer of dentin right next to the DEJ called?

A

Mantle dentin

30
Q

What is responsible for root formation?

A

Hertwig’s epithelial root sheath

31
Q

What makes up the HERS (hertwig’s root sheath)

A

OEEs and IEEs

32
Q

The IEEs of the HERS cause what?

A

Cells in the dental papilla to become odontoblasts that lay down radicular dentin

33
Q

The REEs grow in an apical direction at the cervical loop and become what?

A

HERS (Hertwig’s Epithelial Root Sheath)

34
Q

After radicular dentin is formed what happens to the HERS?

A

It disintegrates and some become remain and become epithelial rests of Malassez

35
Q

What causes the formation of cementoblasts?

A

After the HERS has disintegrated and dental sac cells migrate in and come in contact with the root dentin and that is what causes the dental sac cells to differentiate into cementoblasts

36
Q

What happens to the cementoblasts in the apical 1/2-1/3 of the cementum?

A

They get entrapped and become cementocytes like in bone

37
Q

What gives rise the shape of the root and how many will form?

A

Unequal proliferation of the HERS, just like what gives shape to the crown of the tooth

38
Q

How are the PDLs formed?

A

Ectomesenchyme cells from the dental sac differentiate into fibroblasts that secrete collagen, which become anchored into the cementum

39
Q

How is alveolar bone formed?

A

From the ectomesenchyme cells of the dental sac, PDLs are also anchored into it as well

Oral Bio II (8 decks)

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