Tongue & Salivary Glands Flashcards
Tongue Structures
- Epiglottis
- Lingual and Palatine Tonsils
- Sulcus Terminalis (anterior/posterior)
- Lingual Papillae (4 types)
- Median Sulcus (left/right)
Tongue Composition
Oral Mucosa
Stratified Squamous Epithelium
Connective Tissue
Skeletal Muscle (Oblique, Transverse, Longitudinal)
4 Types of Papillae
Filiform - cone, keratinized, grip, no taste buds
Fungiform - dome, apical taste buds
Foliate - flat top, moats, lateral (2 side) taste buds
Circumvallate - dome, lingual glands, lateral taste buds
Taste Buds Structure
Taste Pore
Sensory Receptor Cell with microvilli (detect tastant)
Supporting Cell (precursors)
Basal Stem Cell
Afferent Nerve Terminal (send signal)
Taste Bud Activation
- tastant binds to taste receptor cell (GPCR)
- Gα dissociate, bind to GTP, open ion channel, ion enter
- depolarize membrane
- release NT onto synapse
3 Major Salivary Glands
- only secrete when signal
Parotid Gland = into parotid duct
Submandibular Gland = into submandibular duct
Sublingual Gland = into mouth
Structure of Salivary Glands
Merocrine
Compound tubulo-acinar
Major Components and Function of Saliva
Buffer Oral Cavity: bicarbonate raise pH
Food Breakdown: amylase –> starch, lipase –> fats
Bacterial Growth: lysozyme (wall), IgA (immune), Lactoferrin (remove iron)
Moisten Food: water
Tooth Mineralization: Ca2+/K+ = protect enamel
Protective Film on Teeth: proteins
Structure of Saliva Secretion
Salivary Gland Acinus
- secretory cells release components into duct
- NaCl and H2O from capillaries
Intercalated Duct
Striated Duct
- produce bicarbonate
- resorb NaCl
Inside a Lobule –> Lobe
Acinus (secretory units)
Intercalated Duct/Intralobular (low cuboidal epithelium)
Striated Duct/Intralobular (simple cuboidal epithelium)
Excretory Duct/Interlobular
Lobar Duct
3 Types of Secretion
Serous Acinus: water+proteins = Paratoid gland
- dark cytoplasm, round basal nuclei, distinct lumen
Mucous Acinus: gel+glycoprotein = Sublingual gland
- light cytoplasm, flat basal nuclei
Mixed Acinus: serous+mucous = Submandibular gland
- serous demilune on top of mucous acinus
Striated Duct
- round central nuclei + basal striations
- basal plasma membrane infolding (regulate saliva)
- parallel mitochondria (resorb NaCl)
Myoepithelial Cells
- surround all acini (stellate shape)
- contract = squeeze serous and mucus acini to release saliva into duct