TLRs Flashcards by Sarah Abdalian | Brainscape

Q

What does TLR1/2 recognize?

Is it intra or extra cellular?

A

GPI= parasites
Bacterial lipopetides

Extracellular

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Q

What does TLR2 recognize?

Is it intra or extra cellular?

A

Bacterial peptidoglycan

Extracellular

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Q

What does TLR4 recognize?

Is it intra or extra cellular?

A

LPS= gram negative bacteria

Extracellular

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Q

What does TLR5 recognize?

Is it intra or extra cellular?

A

Bacterial flagellin

Extracellular

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Q

What does TLR3 recognize?

Is it intra or extra cellular?

A

dsRNA= virus

Intracellular

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Q

What does TLR7 recognize?

Is it intra or extracellular?

A

ssRNA= virus

Intracellular

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Q

What does TLR8 recognize?

Is it intra or extracellular?

A

ssRNA= virus like flu and HIV

Intracellular

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Q

What does TLR9 recognize?

Is it intra or extracellular

A

Unmethylated CpG rich DNA= bacteria and herpes virus

Intracellular

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