TKI Flashcards

1
Q

Axitinib

A

VEGF selective

mRCC

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2
Q

Tivozanib

A

VEGF Selective

IND: r/r RCC

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3
Q

Bevacizumab

A

VEGF selective

IND - HCC w/ atezo

Check for proteinuria

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4
Q

Ramicirumab

A

VEGF selective

R/r HCC, AFP>400

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5
Q

Cabozantinib

A

Nonselective VEGF
KIT, RET, FLT3, AXL, MET

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6
Q

Lenvatinib

A

Nonselective VEGF
KIT, PDGFR, RET, FGFR

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7
Q

Sorafenib

A

Nonselective VEGF
KIT, PDGFR, RET, FLT3

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8
Q

Sunitinib

A

Nonselective VEGF
PDGFR, RET, FLT3

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9
Q

Selpercatinib

A

RET selective

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10
Q

Erdfatinib

A

FGFR2/3 mut bladder CA

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